Sentinel Spectrum

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Description

Sentinel Spectrum, the only beef-flavored chewable to protect against 6 parasites. Sentinel Spectrum prevents heartworms and prevents and controls fleas in a monthly tablet. Each chew also treats and controls whipworms, hookworms, roundworms and tapeworms. Sentinel Spectrum requires a prescription from your veterinarian. Spectrum is for dogs and puppies six weeks of age and older.

Sentinel Spectrum contains Milbemycin Oxime, Praziquantel (offering treatment and control of tapeworms), and Lufenuron (stopping fleas before they become adults, thereby breaking the flea lifecycle). Pillow-shaped chewables facilitate dosing. Each chewable is cured, cut and packaged in a protective blister pack to preserve freshness. 

Benefits

• Tasty beef and bacon chewable treat
• Contains praziquantel to kill tapeworms
• Treats roundworms, hookworms, whipworms and NOW adult tapeworms
• Given once a month to control fleas before they become adults
• Blister-packed to control freshness and stability
• No messy residue to worry about, unlike spot-on treatments
  

Ingredients

Sentinel Spectrum Orange for Dogs 2-8 lbs
Active Ingredient (per chewable tablet)	Amount
Milbemycin Oxime	2.3 mg
Lufenuron	46 mg
Praziquantel	22.8 mg

 

Sentinel Spectrum Green for Dogs 8.1-25 lbs
Active Ingredient (per chewable tablet)	Amount
Milbemycin Oxime	5.75 mg
Lufenuron	115 mg
Praziquantel	57 mg

Sentinel Spectrum Yellow for Dogs 25.1-50 lbs
Active Ingredient (per chewable tablet)	Amount
Milbemycin Oxime	11.5 mg
Lufenuron	230 mg
Praziquantel	114 mg

Sentinel Spectrum Blue for Dogs 50.1-100 lbs
Active Ingredient (per chewable tablet)	Amount
Milbemycin Oxime	23 mg
Lufenuron	460 mg
Praziquantel	228 mg

Directions

Sentinel Spectrum should be administered orally, once every month, at the minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime, 4.55 mg/lb (10 mg/kg) lufenuron, and 2.28 mg/lb (5 mg/kg) praziquantel. For heartworm prevention, give once monthly for at least 6 months after exposure to mosquitoes (see Effectiveness).

Dosage Schedule
Body Weight	Milbemycin Oxime Per Chewable	Lufenuron Per Chewable	Praziquantel Per Chewable	Number of Chewables
2 to 8 lbs	2.3 mg	46 mg	22.8 mg	1 (Orange)
8.1 to 25 lbs	5.75 mg	115 mg	57 mg	1 (Green)
25.1 to 50 lbs	11.5 mg	230 mg	114 mg	1 (Yellow)
50.1 to 100 lbs	23.0 mg	460 mg	228 mg	1 (Blue)
Over 100 lbs	Administer the appropriate combination of chewables

To ensure adequate absorption, always administer Sentinel Spectrum to dogs immediately after or in conjunction with a normal meal.

Sentinel Spectrum may be offered to the dog by hand or added to a small amount of dog food. The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed a few minutes after administration to ensure that no part of the dose is lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.

Heartworm Prevention

Sentinel Spectrum should be administered at monthly intervals beginning within 1 month of the dog’s first seasonal exposure to mosquitoes and continuing until at least 6 months after the dog’s last seasonal exposure (see Effectiveness). Sentinel Spectrum may be administered year-round without interruption. When switching from another heartworm preventative product to Sentinel Spectrum, the first dose of Sentinel Spectrum should be given within a month of the last dose of the former product.

Flea Treatment and Prevention

Treatment with Sentinel Spectrum may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with Sentinel Spectrum should continue the entire year without interruption.

To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product, as necessary.

Intestinal Nematode and Cestode Treatment and Control

Dogs may be exposed to and can become infected with roundworms, whipworms, hookworms, and tapeworms throughout the year, regardless of season or climate. Clients should be advised of appropriate measures to prevent reinfection of their dog with intestinal parasites. Because the prepatent period for E. multilocularis may be as short as 26 days, dogs treated at the labeled monthly intervals may become reinfected and shed eggs between treatments.

Contraindications

There are no known contraindications to the use of Sentinel Spectrum.

Warnings

Not for use in humans. Keep this and all drugs out of the reach of children.

Precautions

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see Effectiveness).

Prior to administration of Sentinel Spectrum, dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. Sentinel Spectrum is not effective against adult D. immitis.

Mild, transient hypersensitivity reactions, such as labored breathing, vomiting, hypersalivation, and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae.

Do not use in puppies less than six weeks of age.

Do not use in dogs or puppies less than two pounds of body weight.

The safety of Sentinel Spectrum has not been evaluated in dogs used for breeding or in lactating females. Studies have been performed with milbemycin oxime and lufenuron alone (see Animal Safety).

Adverse Reactions

The following adverse reactions have been reported in dogs after administration of milbemycin oxime, lufenuron, or praziquantel: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, salivation, and weakness.

To report suspected adverse drug events, contact Virbac at 1-800-338-3659 or the FDA at 1-888-FDA-VETS.

For technical assistance call Virbac at 1-800-338-3659.

Information for Owner or Person Treating Animal

Echinococcus multilocularis and Echinococcus granulosus are tapeworms found in wild canids and domestic dogs. E. multilocularis and E. granulosus can infect humans and cause serious disease (alveolar hydatid disease and hydatid disease, respectively). Owners of dogs living in areas where E. multilocularis or E. granulosus are endemic should be instructed on how to minimize their risk of exposure to these parasites, as well as their dog’s risk of exposure. Although Sentinel Spectrum was 100% effective in laboratory studies in dogs against E. multilocularis and E. granulosus, no studies have been conducted to show that the use of this product will decrease the incidence of alveolar hydatid disease or hydatid disease in humans. Because the prepatent period for E. multilocularis may be as short as 26 days, dogs treated at the labeled monthly intervals may become reinfected and shed eggs between treatments.

Effectiveness

Heartworm Prevention

In a well-controlled laboratory study, Sentinel Spectrum was 100% effective against induced heartworm infections when administered once monthly for 6 consecutive months. In well-controlled laboratory studies, neither one dose nor two consecutive doses of Sentinel Spectrum provided 100% Effectiveness against induced heartworm infections.

Intestinal Nematodes and Cestodes Treatment and Control

Elimination of the adult stage of hookworm (Ancylostoma caninum), roundworm (Toxocara canis, Toxascaris leonina), whipworm (Trichuris vulpis) and tapeworm (Echinococcus multilocularis, Echinococcus granulosus, Taenia pisiformis) infections in dogs was demonstrated in well-controlled laboratory studies.

Flea Prevention and Control

In well-controlled studies, Sentinel Spectrum was effective in preventing flea eggs from hatching, thus providing control of the development of flea populations (Ctenocephalides felis).

Palatability

In a field study of 117 dogs offered Sentinel Spectrum, 113 dogs (96.6%) accepted the product when offered from the hand as if a treat, 2 dogs (1.7%) accepted it from the bowl with food, 1 dog (0.9%) accepted it when it was placed in the dog’s mouth, and 1 dog (0.9%) refused it.

Sentinel Spectrum is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co. Inc.

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by Novartis

Why Sentinel® Spectrum® Chewables?

• Tasty beef and bacon chewable treat
• Contains praziquantel to kill tapeworms
• Treats roundworms, hookworms, whipworms and NOW adult tapeworms
• Given once a month to control fleas before they become adults
• Blister-packed to control freshness and stability
• For dogs six weeks and older

Sentinel Spectrum contains Milbemycin Oxime, Praziquantel (offering treatment and control of tapeworms), and Lufenuron (stopping fleas before they become adults, thereby breaking the flea lifecycle). Pillow-shaped chewables facilitate dosing. Each chewable is cured, cut and packaged in a protective blister pack to preserve freshness. For dogs and puppies six weeks of age and older.