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Trifexis for Dogs
SKU : 114110_-RX
Price: $111.79
Veterinarian Prescription (Rx) Required
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How to Order Prescriptions
TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum milbemycin oxime dose of 0.2 mg/lb (0.5 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions C41H65NO10 and C42H67NO10, respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A3 and A4 of milbemycin oxime. The approximate ratio of A3:A4 is 20:80. Milbemycin A4 5-oxime has the chemical composition of C32H45NO7 and milbemycin A3 5-oxime has the chemical composition of C31H43NO7.
Benefits of Trifexis
Dosage and Administration
Treatment and Control of Intestinal Nematode Infections
In well-controlled laboratory studies, TRIFEXIS was ≥ 90% effective in removing naturally and experimentally induced adult roundworm, whipworm and hookworm infections.
by Elanco
Description
Trifexis for Dogs protects petite dogs from fleas, heartworms, hookworms, roundworms, and whipworms. This FDA-Approved, chewable tablet features a scrumptious beef flavor that makes it easy to administer your pet's monthly dose. By combining spinosad and milbemycin oxide, this treatment combats parasites for a full month and begins working within 30 minutes of administering the first dose.TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum milbemycin oxime dose of 0.2 mg/lb (0.5 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions C41H65NO10 and C42H67NO10, respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A3 and A4 of milbemycin oxime. The approximate ratio of A3:A4 is 20:80. Milbemycin A4 5-oxime has the chemical composition of C32H45NO7 and milbemycin A3 5-oxime has the chemical composition of C31H43NO7.
Benefits of Trifexis
- Kills fleas and prevents infestations.
- Prevents heartworm disease.
- Treats and controls adult hookworm, roundworm, and whipworm infections.
- #1 Prescribed combo parasite protection.
- A monthly, beef-flavored tablet that kills adult fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm, roundworm and whipworm infections.
- Trifexis is proven safe in dogs and puppies 8 weeks and older and 5 pounds and greater.
Trifexis is an ideal choice for
- Families with children or other pets, since there is no transfer of product through contact
- Anyone worried about staining carpeting, clothing or furniture
- Dogs that swim or are bathed frequently
- Dogs with dermatological (skin) conditions requiring topical therapy
View full product label for complete safety information.
Indications
TRIFEXIS is indicated for the prevention of heartworm disease (Dirofilaria immitis). TRIFEXIS kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), and the treatment and control of adult hookworm (Ancylostoma caninum), adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater.Dosage and Administration
TRIFEXIS is given orally, once a month at the minimum
dosage of 13.5 mg/lb (30 mg/kg) spinosad and 0.2 mg/lb (0.5 mg/kg)
milbemycin oxime body weight. For heartworm prevention, give once
monthly for at least 3 months after exposure to mosquitoes (see EFFECTIVENESS).
Dosage Schedule
|
Body Weight |
Spinosad Per Tablet (mg) |
Milbemycin oxime Per Tablet (mg) |
Tablets Administered |
|
5 to 10 lbs |
140 |
2.3 |
One |
|
10.1 to 20 lbs |
270 |
4.5 |
One |
|
20.1 to 40 lbs |
560 |
9.3 |
One |
|
40.1 to 60 lbs |
810 |
13.5 |
One |
|
60.1 to 120 lbs |
1620 |
27 |
One |
|
Over 120 lbs |
Administer the appropriate combination of tablets |
||
Administer TRIFEXIS with food for maximum effectiveness. To ensure heartworm prevention, owners should observe the dog for one hour after dosing. If vomiting occurs within an hour of administration, redose with another full dose. If a dose is messed and a monthly interval between doses is exceeded, then immediate administration of TRIFEXIS with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations.
Heartworm Prevention
TRIFEXIS should be administered at monthly intervals
beginning within 1 month of the dog’s first seasonal exposure and
continuing until at least 3 months after the dog’s last seasonal
exposure to mosquitoes. TRIFEXIS
may be administered year round without interruption. When replacing
another heartworm preventative product, the first dose of TRIFEXIS
should be given within a month of the last dose of the former
medication.
Flea Treatment and Prevention
Treatment with TRIFEXIS may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption.
To minimize the likelihood of flea reinfestation, it is
important to treat all animals within a household with an approved flea
protection product.
Intestinal Nematode Treatment and Control
TRIFEXIS also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis).
Dogs may be exposed to and can become infected with roundworms,
whipworms and hookworms throughout the year, regardless of season or
climate. Clients should be advised of measures to be taken to prevent
reinfection with intestinal parasites.
Effectiveness
Heartworm Prevention
In a well-controlled laboratory study, TRIFEXIS was 100% effective against induced heartworm infections when administered for 3 consecutive monthly doses. Two consecutive monthly doses did not provide 100% effectiveness against heartworm infection. In another well-controlled laboratory study, a single dose of TRIFEXIS was 100% effective against induced heartworm infections. In a well-controlled six-month US field study conducted with TRIFEXIS, no dogs were positive for heartworm infection as determined by heartworm antigen testing performed at the end of the study and again three months later.Flea Treatment and Prevention
In a well-controlled laboratory study, TRIFEXIS demonstrated 100% effectiveness on the first day following treatment and 100% effectiveness on Day 30. In a well-controlled laboratory study, spinosad, a component of TRIFEXIS, began to kill fleas 30 minutes after administration and demonstrated 100% effectiveness within 4 hours. Spinosad, a component of TRIFEXIS, kills fleas before they can lay eggs. If a severe environmental infestation exists, fleas may persist for a period of time after dose administration due to the emergence of adult fleas from pupae already in the environment. In field studies conducted in households with existing flea infestations of varying severity, flea reductions of 98.0% to 99.8% were observed over the course of 3 monthly treatments with spinosad alone. Dogs with signs of flea allergy dermatitis showed improvement in erythema, papules, scaling, alopecia, dermatitis/pyodermatitis and pruritus as a direct result of eliminating the fleas.
Treatment and Control of Intestinal Nematode Infections
In well-controlled laboratory studies, TRIFEXIS was ≥ 90% effective in removing naturally and experimentally induced adult roundworm, whipworm and hookworm infections.Palatability
TRIFEXIS is a flavored chewable tablet. In a field study of client-owned dogs where 175 dogs were each offered TRIFEXIS once a month for 6 months, dogs voluntarily consumed 54% of the doses when offered plain as if a treat, and 33% of the doses when offered in or on food. The remaining 13% of doses were administered like other tablet medications.by Elanco
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How to Order Prescriptions
TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum milbemycin oxime dose of 0.2 mg/lb (0.5 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions C41H65NO10 and C42H67NO10, respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A3 and A4 of milbemycin oxime. The approximate ratio of A3:A4 is 20:80. Milbemycin A4 5-oxime has the chemical composition of C32H45NO7 and milbemycin A3 5-oxime has the chemical composition of C31H43NO7.
Benefits of Trifexis
Dosage and Administration
Treatment and Control of Intestinal Nematode Infections
In well-controlled laboratory studies, TRIFEXIS was ≥ 90% effective in removing naturally and experimentally induced adult roundworm, whipworm and hookworm infections.
by Elanco
Description
Trifexis for Dogs protects petite dogs from fleas, heartworms, hookworms, roundworms, and whipworms. This FDA-Approved, chewable tablet features a scrumptious beef flavor that makes it easy to administer your pet's monthly dose. By combining spinosad and milbemycin oxide, this treatment combats parasites for a full month and begins working within 30 minutes of administering the first dose.TRIFEXIS (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies according to their weight. Each chewable flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg/lb (30 mg/kg) and a minimum milbemycin oxime dose of 0.2 mg/lb (0.5 mg/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions C41H65NO10 and C42H67NO10, respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A3 and A4 of milbemycin oxime. The approximate ratio of A3:A4 is 20:80. Milbemycin A4 5-oxime has the chemical composition of C32H45NO7 and milbemycin A3 5-oxime has the chemical composition of C31H43NO7.
Benefits of Trifexis
- Kills fleas and prevents infestations.
- Prevents heartworm disease.
- Treats and controls adult hookworm, roundworm, and whipworm infections.
- #1 Prescribed combo parasite protection.
- A monthly, beef-flavored tablet that kills adult fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm, roundworm and whipworm infections.
- Trifexis is proven safe in dogs and puppies 8 weeks and older and 5 pounds and greater.
Trifexis is an ideal choice for
- Families with children or other pets, since there is no transfer of product through contact
- Anyone worried about staining carpeting, clothing or furniture
- Dogs that swim or are bathed frequently
- Dogs with dermatological (skin) conditions requiring topical therapy
View full product label for complete safety information.
Indications
TRIFEXIS is indicated for the prevention of heartworm disease (Dirofilaria immitis). TRIFEXIS kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), and the treatment and control of adult hookworm (Ancylostoma caninum), adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater.Dosage and Administration
TRIFEXIS is given orally, once a month at the minimum
dosage of 13.5 mg/lb (30 mg/kg) spinosad and 0.2 mg/lb (0.5 mg/kg)
milbemycin oxime body weight. For heartworm prevention, give once
monthly for at least 3 months after exposure to mosquitoes (see EFFECTIVENESS).
Dosage Schedule
|
Body Weight |
Spinosad Per Tablet (mg) |
Milbemycin oxime Per Tablet (mg) |
Tablets Administered |
|
5 to 10 lbs |
140 |
2.3 |
One |
|
10.1 to 20 lbs |
270 |
4.5 |
One |
|
20.1 to 40 lbs |
560 |
9.3 |
One |
|
40.1 to 60 lbs |
810 |
13.5 |
One |
|
60.1 to 120 lbs |
1620 |
27 |
One |
|
Over 120 lbs |
Administer the appropriate combination of tablets |
||
Administer TRIFEXIS with food for maximum effectiveness. To ensure heartworm prevention, owners should observe the dog for one hour after dosing. If vomiting occurs within an hour of administration, redose with another full dose. If a dose is messed and a monthly interval between doses is exceeded, then immediate administration of TRIFEXIS with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations.
Heartworm Prevention
TRIFEXIS should be administered at monthly intervals
beginning within 1 month of the dog’s first seasonal exposure and
continuing until at least 3 months after the dog’s last seasonal
exposure to mosquitoes. TRIFEXIS
may be administered year round without interruption. When replacing
another heartworm preventative product, the first dose of TRIFEXIS
should be given within a month of the last dose of the former
medication.
Flea Treatment and Prevention
Treatment with TRIFEXIS may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption.
To minimize the likelihood of flea reinfestation, it is
important to treat all animals within a household with an approved flea
protection product.
Intestinal Nematode Treatment and Control
TRIFEXIS also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis).
Dogs may be exposed to and can become infected with roundworms,
whipworms and hookworms throughout the year, regardless of season or
climate. Clients should be advised of measures to be taken to prevent
reinfection with intestinal parasites.
Effectiveness
Heartworm Prevention
In a well-controlled laboratory study, TRIFEXIS was 100% effective against induced heartworm infections when administered for 3 consecutive monthly doses. Two consecutive monthly doses did not provide 100% effectiveness against heartworm infection. In another well-controlled laboratory study, a single dose of TRIFEXIS was 100% effective against induced heartworm infections. In a well-controlled six-month US field study conducted with TRIFEXIS, no dogs were positive for heartworm infection as determined by heartworm antigen testing performed at the end of the study and again three months later.Flea Treatment and Prevention
In a well-controlled laboratory study, TRIFEXIS demonstrated 100% effectiveness on the first day following treatment and 100% effectiveness on Day 30. In a well-controlled laboratory study, spinosad, a component of TRIFEXIS, began to kill fleas 30 minutes after administration and demonstrated 100% effectiveness within 4 hours. Spinosad, a component of TRIFEXIS, kills fleas before they can lay eggs. If a severe environmental infestation exists, fleas may persist for a period of time after dose administration due to the emergence of adult fleas from pupae already in the environment. In field studies conducted in households with existing flea infestations of varying severity, flea reductions of 98.0% to 99.8% were observed over the course of 3 monthly treatments with spinosad alone. Dogs with signs of flea allergy dermatitis showed improvement in erythema, papules, scaling, alopecia, dermatitis/pyodermatitis and pruritus as a direct result of eliminating the fleas.
Treatment and Control of Intestinal Nematode Infections
In well-controlled laboratory studies, TRIFEXIS was ≥ 90% effective in removing naturally and experimentally induced adult roundworm, whipworm and hookworm infections.Palatability
TRIFEXIS is a flavored chewable tablet. In a field study of client-owned dogs where 175 dogs were each offered TRIFEXIS once a month for 6 months, dogs voluntarily consumed 54% of the doses when offered plain as if a treat, and 33% of the doses when offered in or on food. The remaining 13% of doses were administered like other tablet medications.by Elanco
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