Altren (altrenogest) (generic Regu-Mate)

Description

Altren® (altrenogest) Oral Solution is a prescription synthetic progestin indicated for the suppression of estrus (heat) in mares. As a cost-effective generic alternative to Regu-Mate®, Altren contains the same active ingredient and concentration to help veterinarians and horse owners effectively manage reproductive cycles.

Suppressing estrus allows for a more predictable return to heat following treatment, making it easier to schedule breeding, manage prolonged estrus, and support mares transitioning into the breeding season. The ready-to-use oral solution is supplied in a 1,000 mL bottle with a dispensing cap for convenient, accurate daily dosing.

Uses & Benefits

• Suppresses estrus (heat) in mares
• Helps establish predictable estrous cycles
• Facilitates scheduled breeding programs
• Assists in managing prolonged estrus
• Supports mares transitioning from winter anestrus to the breeding season
• Same active ingredient and strength as Regu-Mate®
• Convenient once-daily oral dosing
• Includes dispensing cap for accurate administration

How It Works

Altren® contains altrenogest, a synthetic progestin that suppresses estrus by mimicking the effects of the natural hormone progesterone. During treatment, mares remain out of heat, allowing estrous cycles to be managed more predictably. After the treatment period ends, mares typically return to estrus in a controlled timeframe, making breeding management easier.

Indications

Altren® is indicated for the suppression of estrus in mares. Suppression of estrus may be used to:

• Schedule breeding during the physiological breeding season
• Manage prolonged estrus conditions
• Promote regular cyclicity during the transition from winter anestrus
• Improve breeding management and performance scheduling

Ingredients

Active Ingredients:

Altrenogest 2.2 mg/mL (0.22%)

Inactive Ingredients:

Oil-based vehicle

(The complete inactive ingredient formulation is proprietary.)

Directions

Wear protective gloves before handling the product.
Administer 1 mL per 110 lb (0.044 mg/kg) of body weight orally once daily for 15 consecutive days.
The solution may be administered directly onto the base of the mare's tongue or applied to the mare's normal grain ration.

Use the supplied dispensing cap and an appropriate oral dosing syringe for accurate measurement.
Follow your veterinarian's instructions for proper administration.

Weight & Dosage

Dosage: 1 mL per 110 lb (0.044 mg/kg) of body weight once daily for 15 consecutive days.
Approximate dosage guide:

Always follow your veterinarian's prescribed dosing regimen.

Cautions

• Federal law restricts this drug to use by or on the order of a licensed veterinarian.
• For use in mares only.
• Do not use in horses intended for human consumption.
• Women who are pregnant, may become pregnant, or have hormone-dependent medical conditions should avoid contact with this product.
• Wear protective gloves when handling and administering the solution.
• Wash exposed skin immediately if accidental contact occurs.
• Keep out of reach of children and animals.

Possible Side Effects

When used as directed, side effects in mares are uncommon. Accidental human exposure may cause hormonal effects.

If a mare develops an unexpected reaction or fails to respond to treatment, consult your veterinarian promptly.

Precautions

Handle carefully to avoid accidental skin exposure.
Always wear protective gloves during dosing.
Use caution when measuring or transferring the solution to prevent spills.
Follow all veterinarian recommendations regarding breeding schedules and treatment duration.
Store and dispose of the product according to label directions.

Storage

Store at or below 77°F (25°C). Keep the bottle tightly closed when not in use. Store in the original container with the dispensing cap securely attached. Dispose of empty containers, gloves, and contaminated materials according to local regulations. Keep out of reach of children and animals.