Amantadine Compounded Soft Chews are a prescription medication prepared specifically for an individual dog or cat according to a veterinarian’s directions. Amantadine may be prescribed as an adjunctive medication for chronic pain, particularly when central sensitization or neuropathic pain contributes to ongoing discomfort.
Amantadine may be incorporated into a multimodal pain-management program for pets with osteoarthritis-associated pain, neurological pain, or other persistent painful conditions. The soft chew formulation provides a convenient option for veterinarian-directed administration.
Amantadine acts as an N-methyl-D-aspartate (NMDA) receptor antagonist. NMDA receptors are involved in central sensitization, a process in which persistent stimulation can cause the nervous system to become increasingly responsive to pain signals.
By affecting NMDA receptor activity, amantadine may help reduce the amplification of persistent pain signals. In veterinary medicine, it is generally used as an adjunct to other appropriate pain-management therapies rather than as a stand-alone analgesic.
For veterinarian-directed use in dogs and cats as part of an individualized pain-management program.
Amantadine may be prescribed as an adjunct for:
Use of amantadine for pain management in dogs and cats is extra-label and should be directed by a licensed veterinarian.
Active Ingredients:
Amantadine
Inactive Ingredients:
Beef Steak Flavor / Refer to pharmacy label for complete inactive ingredient information
Administer orally exactly as prescribed by your veterinarian.
Give the prescribed amount according to your veterinarian’s instructions. This medication is compounded specifically for the individual pet based on the veterinary prescription.
Soft chews are individually sealed in blister packaging. Remove the prescribed chew from the blister when ready to administer and keep unused chews in their original packaging.
Dosage is individualized according to the pet’s species, body weight, condition, response to therapy, and other medications being administered.
Do not change the prescribed amount, frequency, or duration of treatment unless directed by your veterinarian.
Follow the prescription label exactly and veterinarian directions.
Gastrointestinal Upset / Diarrhea / Flatulence / Agitation / Restlessness
Contact your veterinarian if side effects are persistent or severe or if your pet develops significant behavioral changes or another unexpected reaction.
Use cautiously in animals with impaired kidney function because amantadine is primarily eliminated through the kidneys.
Tell your veterinarian about all prescription medications, non-prescription medications, supplements, and other pain-management products your pet receives.
Veterinary supervision is important when amantadine is administered with other medications that affect the central nervous system.
Chronic pain should be periodically reassessed by a veterinarian because treatment requirements may change over time.
Consult your veterinarian regarding use in pregnant, breeding, or nursing animals.
Do not change the prescribed dose or administration frequency without veterinary direction.
Store at room temperature. Refrigeration is not required. Keep soft chews in their individually sealed blister packaging until ready to administer. Protect from excessive heat and moisture and follow the pharmacy label for complete storage requirements.
Disposal
Dispose of unused or expired Amantadine Compounded Soft Chews through a medication take-back program when available or according to applicable local medication disposal requirements. Do not give leftover medication to another animal. Keep discarded medication and packaging securely inaccessible to children and animals.