Enroflox 100 (enrofloxacin) Antimicrobial Injection Solution

Enroflox 100 (enrofloxacin) Antimicrobial Injection Solution
100mL - injectable solution
SKU : 289100_-RX
Price: $77.95
Price: $77.95

Veterinarian Prescription (Rx) Required
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  • Treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle; and for the control of BRD associated with M. haemolytica, P. multocida, H. somni and M. bovis. 
  • Treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni in beef and non-lactating dairy cattle.
  • Treatment and control of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, Streptococcus suis, Bordetella bronchiseptica and Mycoplasma hyopneumoniae. Enroflox 100 is indicated for the control of colibacillosis in groups or pens of weaned pigs where colibacillosis associated with Escherichia coli has been diagnosed.

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Description

Enroflox 100 (enrofloxacin) Antimicrobial Injection Solution is for subcutaneous use in beef cattle and non-lactating dairy cattle, for intramuscular or subcutaneous use in swine. 

Cattle - Single Dose Therapy

Enroflox 100 is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle; and for the control of BRD associated with M. haemolytica, P. multocida, H. somni and M. bovis. 

Cattle - Multiple-Day Therapy 

Enroflox 100 is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni in beef and non-lactating dairy cattle.

Swine

Enroflox 100 is indicated for the treatment and control of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, Streptococcus suis, Bordetella bronchiseptica and Mycoplasma hyopneumoniae. Enroflox 100 is indicated for the control of colibacillosis in groups or pens of weaned pigs where colibacillosis associated with Escherichia coli has been diagnosed.

Dosage and Administration

Enroflox 100 provides flexible dosages and durations of therapy, Enroflox 100 may be administered as a single dose for one day treatment and control of BRD (cattle), for treatment and control of SRD or for the control of colibacillosis (swine), or for multiple days of BRD treatment (cattle). Selection of the appropriate dose and duration of therapy of BRD treatment in cattle should be based on an assessment of the severity of the disease, pathogen susceptibility and clinical response. 

Cattle

Single-Dose Therapy (BRD Treatment)

Administer, by subcutaneous injection, a single dose of 7.5-12.5 mg/kg of body weight (3.4-5.7 mL/100lb).

Multiple-Day Therapy  (BRD Treatment)

Administer daily, a subcutaneous dose of 2.5-5mg/kg of body weight (1.1-2.3 mL/100 lb). Treatment should be repeated at 24-hour intervals for three days. Additional treatments may be given on Days 4 and 5 to animals that have shown clinical improvement but not total recovery.

Single Dose Therapy (BRD Control)

Administer, by subcutaneous injection, a single dose of 7.5mg/kg of body weight (3.4mL/100 lb). Examples of conditions that may contribute to calves being at high risk for developing BRD include, but not limited to, the following:
  • Transportation with animals from two or more farm origins. 
  • An extended transport time with few to no rest stops.
  • An environmental temperature change of > or + 30º Fahrenheit during transportation.
  • Exposure to wet or cold weather conditions.
  • Excessive shrink (more than would be expected with a normal load of cattle).
  • Stressful arrival processing procedures (e.g., castration or dehorning).
  • Exposure within the prior 72 hours to animals showing clinical signs of BRD.
Administered dose volume should not exceed 20 mL per injection site. 
  Treatment  Control 
       Weight (lb)               Single-Dose Therapy 7.5 - 12.5 mg/kg Dose Volume (mL)                Multiple-Dose Therapy 2.5 - 5.0 mg/kg Dose Volume (mL)        Single-Dose Therapy 7.5mg/kg Dose Volume (mL)
 100  3.5-5.5 1.5-2.0  3.5
 200   7.0-11.0 2.5-4.5  7.0 
 300 10.5-17.0  3.5-6.5  10.5 
 400 14.0-22.5  4.5-9.0  14.0 
 500 17.0-28.5  5.5-11.5  17.0 
 600 20.5-34.0  7.0-13.5  20.5 
 700 24.0-39.5  8.0-16.0  24.0 
 800 27.5-45.5  9.0-18.0  27.5 
 900 31.0-51.0  10.0-20.5  31.0 
 1000 34.0-57.0  11.0-23.0  34.0 
 1100 37.5-62.5  12.5-25.0  37.5 
*Dose volumes have been rounded to the nearest 0.5mL within the dose range.

Swine

Administer, either by intramuscular or subcutaneous (behind the ear) injection, a single dose of 7.5mg/kg of body weight (3.4mL/100lb). Administered dose volume should not exceed 5 mL per injection site.

For the control of colibacillosis, administration should be initiated within the first 60 days post-weaning when clinical signs are present in at least 2% of the animals in the group. If no improvement is noted within 48 hours, the diagnosis should be reevaluated. 

    Weight (lb)      Dose Volume (mL)
15 0.5
30 1.0
50 1.7
100 3.4
150 5.1
200 6.8
250 8.5
Dilution of Enroflox 100: Enroflox 100 may be diluted with sterile water prior to injection. The diluted product should be used within 24 hours. Stores diluted solution in amber glass bottles between 4º Celsius to 40º Celsius (36º Fahrenheit to 104º Fahrenheit). 

   Swine Weight        mL of Enroflox 100       mL of sterile water       Number of doses   
10 lb 34 mL 66 mL 100 
15 lb 51 mL 49 mL 100
20 lb 68 mL  32 mL 100
25 lb 85 mL 15 mL 100
*For 1 mL dose volume from diluted solution

100 mL vial

Use within 30 days of first puncture and puncture a maximum of 36 times. When using a needle or draw-off spike larger than 16 gauge, discard any remaining product immediately after use.

250 mL and 500 mL vials

Use within 30 days of first puncture. Puncture a maximum of 36 times with a needle or dosage delivery device 16 gauge or smaller, 4 times with a draw-off spike 5mm or smaller. When using a needle larger than 16 gauge, or a draw-off spike larger than 5mm, discard any remaining product immediately after use.

Warnings

Not for the use in humans. Keep out of reach of children. Avoid contact with eyes. In case of contact, immediately flush eyes with copious amounts of water for 15 minutes. In case of dermal contact, wash skin with soap and water. Consult a physician if irritation persists following ocular or dermal exposures. Individuals with a history of hypersensitivity to quinolones should avoid this product. In humans, there is a risk of user photosensitization within a few hours after excessive exposure to quinolones. If excessive accidental exposure occurs, avoid direct sunlight.  

Storage

Protect from direct sunlight. Do not refrigerate or freeze. Store below 77º F (25º C). Precipitation may occur due to cold temperature. To redissolve, warm and then shake the vial. 
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