Cyproheptadine Compounded Transdermal

Description

Cyproheptadine Compounded Transdermal is a prescription medication prepared for veterinarian-directed use in pets. Cyproheptadine is an antihistamine with serotonin-antagonist properties and may be prescribed extra-label in veterinary medicine for appetite stimulation, particularly in cats, and for other conditions where its pharmacologic effects are appropriate.

The compounded transdermal formulation is applied to the skin of the ear and provides an alternative dosage form for pets that are difficult to medicate orally. Because this is a compounded medication, use and dosing should be individualized by the prescribing veterinarian.

Uses & Benefits

• May be prescribed to stimulate appetite, particularly in cats
• Provides antihistamine activity
• Provides serotonin-antagonist activity
• May be prescribed for certain veterinarian-diagnosed conditions involving excessive serotonergic activity
• Transdermal administration provides an alternative to oral medication
• Helpful for pets that are difficult to medicate by mouth
• Compounded according to an individual veterinary prescription

How It Works

Cyproheptadine is a first-generation antihistamine with histamine H1 receptor antagonist and serotonin receptor antagonist activity. Its appetite-stimulating effects are associated primarily with antagonism of serotonin receptors involved in appetite regulation.

Indications

Appetite Stimulation / Veterinarian-Directed Management of Certain Allergic Conditions / Certain Serotonin-Related Toxicities

Veterinary use of cyproheptadine is extra-label and should be determined by the prescribing veterinarian based on the individual animal's condition.

Ingredients

Active Ingredients:

Cyproheptadine Hydrochloride

Inactive Ingredients:

Refer to manufacturer label for complete inactive ingredient information.

Directions

Follow the prescription label exactly and veterinarian directions.

Apply the prescribed amount of medication to the skin of the ear as directed on the prescription label.

Wear gloves or use appropriate protection when applying transdermal medication to avoid accidental human exposure. Apply only to the location directed by the veterinarian or dispensing pharmacy.

Do not allow other animals or people to lick or contact the application site until the medication has been absorbed or as otherwise directed.

Do not change the amount, frequency, or application method without veterinarian direction.

Cautions

• For veterinary use only.
• Prescription medication.
• Use only under the direction of a licensed veterinarian.
• Do not use in animals with known hypersensitivity to cyproheptadine.
• Use cautiously in geriatric animals and animals with glaucoma, urinary obstruction, gastrointestinal obstruction, severe cardiovascular disease, seizures, hyperthyroidism, or prostatic enlargement.
• Tell your veterinarian about all medications and supplements your pet receives before starting treatment.
• Cyproheptadine may interact with monoamine oxidase inhibitors, central nervous system depressants, and other medications.
• Avoid accidental human exposure to the compounded transdermal medication.
• Wash hands thoroughly after application, even if gloves are worn.
• Keep out of reach of children and animals.

Possible Side Effects

Drowsiness or Sedation / Increased Appetite / Dry Mouth / Excitability or Restlessness / Vomiting / Diarrhea / Decreased Appetite

Contact your veterinarian if side effects are persistent, severe, or concerning.

Precautions

Cyproheptadine is prescribed extra-label in veterinary medicine. Treatment recommendations should be individualized according to the animal's condition and response to therapy.

Use cautiously in animals with liver or kidney disease because the effects of cyproheptadine may be prolonged. Safety in pregnant or lactating animals has not been thoroughly established.

Provide the veterinarian with a complete list of medications and supplements before treatment because clinically significant drug interactions may occur.

Transdermal preparations are compounded formulations, and absorption may differ from oral formulations. Do not substitute one dosage form for another unless specifically directed by the prescribing veterinarian.

Storage

Store according to the instructions on the prescription label. Because this is a compounded preparation, storage requirements and beyond-use dates may vary according to the formulation. Keep the container securely closed and protect from excessive heat, moisture, and direct light as directed by the dispensing pharmacy.

Disposal

Dispose of unused or expired Cyproheptadine Compounded Transdermal through a medication take-back program when available or according to applicable local medication disposal requirements. Keep discarded medication and packaging securely inaccessible to children and animals.