Posatex Otic Suspension

Posatex Otic Suspension
Small 7.5g - plastic bottle
Medium 15g - plastic bottle
Large 30g - plastic bottle
SKU : 610375_-RX
Price: $22.25
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by Merck Animal Health

1.0% Orbifloxacin, 0.1% Mometasone Furoate Monohydrate and 0.1% Posaconazole, Otic Suspension

  • Antibacterial
  • Anti-inflammatory
  • Antifungal

For Otic Use in Dogs Only

INDICATIONS: POSATEX™ Otic Suspension is indicated for the treatment of otitis externa in dogs associated with susceptible strains of yeast (Malassezia pachydermatis) and bacteria (coagulase positive staphylococci, Pseudomonas aeruginosa, and Enterococcus faecalis).

DOSAGE AND ADMINISTRATION: Shake well before use. For dogs weighing less than 30 lbs. instill 4 drops of POSATEX™ Otic Suspension once daily into the ear canal. For dogs weighing 30 lbs. or more, instill 8 drops once daily into the ear canal. Therapy should continue for 7 consecutive days.

EFFECTIVENESS: The effectiveness of POSATEX™ Otic Suspension was evaluated in a placebo-controlled, double-blind, multi-site field study. One hundred and ninety one dogs with naturally occurring clinical otitis externa associated with both yeast and bacteria were randomly allocated to either POSATEX™ Otic Suspension or placebo ointment. Of the 160 dogs evaluated for effectiveness, 122 were treated with POSATEX™ Otic Suspension and 38 were treated with placebo ointment. Treatments were administered once daily for 7 consecutive days. Assessment of effectiveness was based on improvement in clinical signs at re-evaluation 2-7 days following administration of the last dose.

Compared to the placebo, a significant percent of dogs treated with POSATEX™ Otic Suspension showed improvement in clinical signs (discomfort, erythema, and swelling) caused by otitis externa associated with one or more of the following organisms: Malassezia pachydermatis , coagulase positive staphylococci, Pseudomonas aeruginosa , and Enterococcus faecalis .

Percent of Dogs Showing Improvement in Clinical Signs of Otitis Externa

Clinical Sign

POSATEX™ Otic Suspension Group

Placebo Group

Significance

Discomfort

88%

45%

p<0.0001

External Ear Canal Erythema

81%

39%

p<0.0001

External Ear Canal Swelling

83%

49%

p=0.0001

ANIMAL SAFETY: POSATEX™ Otic Suspension was administered at 1,3, and 5 times the recommended dosage for 21 consecutive days. The control group received the vehicle in both ears at the clinical dose given five times per day. There was a slight decrease in serum cortisol concentration a er ACTH stimulation on Day 21 in the 5X group. Erythema was noted in all groups. Aural pain, swelling, or heat were each noted in 3 separate dogs in the 5X group.

Customer Reviews
(5.00)
# of Ratings: 1
1. on 11/19/2010, said:
My lab poodle mix has cronic ear infections, primarily yeast. They are hard to clear, and come back. This product cleared the infection in about 4 days, and he has gone weeks without recurrence. Much better results than Otomax for his condition.
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by Intervet

1.0% Orbifloxacin, 0.1% Mometasone Furoate Monohydrate and 0.1% Posaconazole, Otic Suspension

  • Antibacterial
  • Anti-inflammatory
  • Antifungal

For Otic Use in Dogs Only

INDICATIONS: POSATEX™ Otic Suspension is indicated for the treatment of otitis externa in dogs associated with susceptible strains of yeast (Malassezia pachydermatis) and bacteria (coagulase positive staphylococci, Pseudomonas aeruginosa, and Enterococcus faecalis).

DOSAGE AND ADMINISTRATION: Shake well before use. For dogs weighing less than 30 lbs. instill 4 drops of POSATEX™ Otic Suspension once daily into the ear canal. For dogs weighing 30 lbs. or more, instill 8 drops once daily into the ear canal. Therapy should continue for 7 consecutive days.

EFFECTIVENESS: The effectiveness of POSATEX™ Otic Suspension was evaluated in a placebo-controlled, double-blind, multi-site field study. One hundred and ninety one dogs with naturally occurring clinical otitis externa associated with both yeast and bacteria were randomly allocated to either POSATEX™ Otic Suspension or placebo ointment. Of the 160 dogs evaluated for effectiveness, 122 were treated with POSATEX™ Otic Suspension and 38 were treated with placebo ointment. Treatments were administered once daily for 7 consecutive days. Assessment of effectiveness was based on improvement in clinical signs at re-evaluation 2-7 days following administration of the last dose.

Compared to the placebo, a significant percent of dogs treated with POSATEX™ Otic Suspension showed improvement in clinical signs (discomfort, erythema, and swelling) caused by otitis externa associated with one or more of the following organisms: Malassezia pachydermatis , coagulase positive staphylococci, Pseudomonas aeruginosa , and Enterococcus faecalis .

Percent of Dogs Showing Improvement in Clinical Signs of Otitis Externa

Clinical Sign

POSATEX™ Otic Suspension Group

Placebo Group

Significance

Discomfort

88%

45%

p<0.0001

External Ear Canal Erythema

81%

39%

p<0.0001

External Ear Canal Swelling

83%

49%

p=0.0001

ANIMAL SAFETY: POSATEX™ Otic Suspension was administered at 1,3, and 5 times the recommended dosage for 21 consecutive days. The control group received the vehicle in both ears at the clinical dose given five times per day. There was a slight decrease in serum cortisol concentration a er ACTH stimulation on Day 21 in the 5X group. Erythema was noted in all groups. Aural pain, swelling, or heat were each noted in 3 separate dogs in the 5X group.

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