Additional adjunctive therapy should be used when indicated. Most susceptible infectious disease organisms will respond to chloramphenicol therapy in three to five days when the recommended dosage regime is followed. If no response to chloramphenicol therapy is obtained in three to five days, discontinue its use and review the diagnosis. Also, a change of therapy should be considered.
Laboratory tests should be conducted including in vitro culturing and susceptibility tests on samples collected prior to treatment.Chloramphenicol may be recommended for bacterial infections caused by susceptible organisms, including:
Respiratory infections caused by organisms such as Staphylococcus aureus, Streptococcus pyogenes, and Bordetella bronchiseptica
Urinary tract infections involving Escherichia coli, Proteus vulgaris, Corynebacterium renale, Streptococcus spp., and others
Intestinal infections due to E. coli, Salmonella spp., Proteus spp., and Pseudomonas spp.
Infections related to canine distemper involving pathogens like B. bronchiseptica, P. aeruginosa, Shigella spp., and Neisseria catarrhalis
Treatment response is often observed within 3 to 5 days when the recommended dosage is followed. If improvement is not seen, consult your veterinarian to reassess the diagnosis or treatment approach.
Not for human use
Not for use in animals intended for food production
Should not be used in breeding dogs
Use caution when combining with other medications—chloramphenicol may interfere with drugs like penicillin or streptomycin
Do not administer within two hours of general anesthesia using pentobarbital
Some pets may experience temporary digestive upset, including vomiting or diarrhea
Keep tightly sealed in a dry place at or below 25°C (77°F). Store out of reach of children and pets.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.