Ivomec Eprinex

Ivomec Eprinex Cattle Wormer
Pour-On, 250ml - 250ml
Pour-On, 1L - 1 liter
Pour-On, 2.5L - 2.5 liters
Pour-On, 5L - 5 liters
SKU : 1004250
Price: $46.95

(eprinomectin)

  • Pour-On for Beef and Dairy Cattle 
  • Eprinomectin pour-on for internal and external parasites in beef and dairy cattle

This item not available for sale or shipment to California residents.

*Manufacturer restricts additional discounts on this item unless explicitly specified

Description

IVOMEC EPRINEX is the most potent parasite control product ever produced. 
    • Only IVOMEC EPRINEX is more than 99% effective against 11 economically damaging internal parasites, including the brown stomach worm. 
    • More than 99% effective against 12 damaging fourth-stage immature larvae. 
    • Wipes out the larvae before they're old enough to lay eggs. 
    • Kills a broader spectrum of parasites than any other pour-on. 
    • And it controls biting and sucking lice. 
    • IVOMEC EPRINEX controls up to twice as many stages as its competitors.
    • This broad-spectrum control can lead to:
      • Better weight gains
      • Improved reproductive performance
      • Better feed conversion
      • Reduced pasture contamination
      • Healthier cattle that look better 
IVOMEC EPRINEX features a weather-proof formulation. 
    • Research shows that IVOMEC EPRINEX is more than 99% effective - even on wet cattle. 
    • Works anytime - perfect for your busy schedule. 
    • It's pour-on applicator makes dosing easy and accurate. 
    • And, it's ordorless, non-flammable formula eliminates the need for clumsy protect gear. 
University studies have proven that internal parasites can cause a suppressed immune response. 
    • Parasites interfere with the animal's ability to develop an adequate immune response to vaccination. 
    • And respiratory and reproductive diseases create significant costs in lost opportunity for the beef industry. 
    • Animals affected by these conditions suffers from poor performance, higher costs, reduced gain, and in some cases, lower quality. 
    • Additional costs from death loss and medical expenses reduce the bottom line. Parasite and disease programs help prevent sickness and poor performance. 
    • Internal and external parasite control is an important aspect of the Merial® SureHealth Program. 
    • In the SureHealth program, parasite control, immunization and preconditioning steps are done by the producer and documented by a participating veterinarian. 
    • One of Merial's leading parasiticide products is IVOMEC EPRINEX. 
    • IVOMEC EPRINEX is easy to apply and goes right to work.


by Merial
Customer Reviews
(0.00)
# of Ratings: 0

IVOMEC® EPRINEX® POUR-ON FOR BEEF AND DAIRY CATTLE

Merial

(eprinomectin)

NADA 141-079, Approved by the FDA

Parasiticide

Contains 5 mg eprinomectin/mL

INTRODUCTION

IVOMEC EPRINEX Pour-On delivers highly effective internal and external parasite control in one application. Discovered and developed by scientists from Merck Research Laboratories, IVOMEC EPRINEX Pour-On contains eprinomectin, a unique avermectin. Its broad-spectrum efficacy in a weatherproof formulation, margin of safety, zero slaughter withdrawal and zero milk discard, make it a convenient product for parasite control in beef and dairy cattle, including lactating dairy cattle.

MODE OF ACTION

Eprinomectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells.

This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).

The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.

INDICATIONS

IVOMEC EPRINEX (eprinomectin) Pour-On is indicated for the treatment and control of gastrointestinal roundworms (including inhibited Ostertagia ostertagi), lungworms, grubs, sucking and biting lice, chorioptic and sarcoptic mange mites, and horn flies in beef and dairy cattle of all ages, including lactating dairy cattle.

Applied at the recommended dose volume of 1 mL/10 kg (22 lb) body weight, to achieve a dose level of 500 mcg eprinomectin/kg body weight, IVOMEC EPRINEX Pour-On is indicated for the effective treatment and control of the following parasites.

Gastrointestinal Roundworms

Haemonchus placei (adults and L4)

Ostertagia ostertagi (including inhibited L4) (adults and L4)

Trichostrongylus axei (adults and L4)

Trichostrongylus colubriformis (adults and L4)

Trichostrongylus longispicularis (adults only)

Cooperia oncophora (adults and L4)

Cooperia punctata (adults and L4)

Cooperia surnabada (adults and L4)

Nematodirus helvetianus (adults and L4)

Oesophagostomum radiatum (adults and L4)

Bunostomum phlebotomum (adults and L4)

Strongyloides papillosus (adults only)

Trichuris spp. (adults only)

Lungworms

Dictyocaulus viviparus (adults and L4)

Cattle Grubs (all parasitic stages)

Hypoderma lineatum

Hypoderma bovis

Lice

Damalinia bovis

Linognathus vituli

Haematopinus eurysternus

Solenopotes capillatus

Mange Mites

Chorioptes bovis

Sarcoptes scabiei

Horn Flies

Haematobia irritans

Persistent Activity

IVOMEC EPRINEX (eprinomectin) Pour-On for Beef and Dairy Cattle has been proved to effectively control infections and to protect cattle from re-infection with Dictyocaulus viviparus for 21 days after treatment and Haematobia irritans for 7 days after treatment.

Use Conditions

Varying weather conditions, including rainfall, do not affect the efficacy of IVOMEC EPRINEX Pour-On.

Management Considerations for Treatment of External Parasites

For best results IVOMEC EPRINEX Pour-On should be applied to all cattle in the herd. Cattle introduced to the herd later should be treated prior to introduction. Consult your veterinarian or an entomologist for the most effective timing of applications for the control of external parasites.

Chorioptic Mange: In clinical studies evaluating the efficacy of IVOMEC EPRINEX Pour-On against chorioptic mange mites, mites were not recovered from skin scrapings taken 8 weeks after treatment; however, chronic skin lesions were still present on some animals.

Horn flies: For optimal control of horn flies, as IVOMEC EPRINEX Pour-On provides 7 days of persistent activity against horn flies, the product should be used as part of an integrated control program utilizing other control methods to provide extended control.

DOSAGE

The product is formulated only for external application to beef and dairy cattle. The dose rate is 1 mL/10 kg (22 lb) of body weight. The product should be applied topically along the backline in a narrow strip extending from the withers to the tailhead.

ADMINISTRATION

Squeeze-Measure-Pour System (250 mL/8.5 fl oz Bottle with 25 mL Metering Cup)

Attach the metering cup to the bottle.

Set the dose by turning the top section of the cup to align the correct body weight with the pointer on the knurled cap. When body weight is between markings, use the higher setting.

Hold the bottle upright and squeeze it to deliver a slight excess of the required dose as indicated by the calibration lines. By releasing the pressure, the dose automatically adjusts to the correct level. The off (STOP) position will close the system between dosing. Tilt the bottle to deliver the dose.

Squeeze-Measure-Pour System (1 L/33.8 fl oz Bottle with 50 mL Metering Cup)

Attach the metering cup to the bottle.

Set the dose by turning the top section of the cup to align the correct body weight with the pointer on the knurled cap. When body weight is between markings, use the higher setting.

Hold the bottle upright and squeeze it to deliver a slight excess of the required dose as indicated by the calibration lines.

By releasing the pressure, the dose automatically adjusts to the correct level. When a 220 lb (10 mL) or 330 lb (15 mL) dose is required, turn the pointer to “STOP” before delivering the dose. The off (STOP) position will close the system between dosing. Tilt the bottle to deliver the dose.

Collapsible Pack (2.5 L/84.5 fl oz and 5 L/169 fl oz Packs)

Connect the dosing applicator and draw-off tubing to the collapsible pack as follows:

Attach the open end of the draw-off tubing to an appropriate dosing applicator. Attach draw-off tubing to the cap with the stem that is included in the pack. Replace the shipping cap with the cap having the draw-off tubing.

Gently prime the dosing applicator, checking for leaks. Follow the dosing applicator manufacturer’s directions for adjusting the dose and proper use and maintenance of the dosing applicator and draw-off tubing.

20 Liter Pack (20 L/676 fl oz Pack)

Connect the dosing applicator and draw-off tubing to the container as follows:

Attach the open end of the draw-off tubing to an appropriate dosing applicator. Attach draw-off tubing to the cap with the stem. Replace the shipping cap with the cap having the draw-off tubing.

Gently prime the dosing applicator, checking for leaks. Follow the dosing applicator manufacturer’s directions for adjusting the dose and proper use and maintenance of the dosing applicator and draw-off tubing.

ANIMAL SAFETY

Tolerance and toxicity studies have demonstrated the margin of safety for eprinomectin in cattle. In toxicity studies, application of 3 times the recommended dose had no adverse effects on neonatal calves, and application of up to 5 times the recommended dose 3 times at 7 day intervals had no adverse effects on 8 week old calves. In the tolerance study, one of 6 cattle treated once at 10 times the recommended dose showed clinical signs of mydriasis. Application of 3 times the recommended dose had no adverse effect on breeding performance of cows or bulls.

Residue Information: When used according to label directions, neither a pre-slaughter drug withdrawal period nor a milk discard time is required, therefore, meat and milk from cattle treated with IVOMEC EPRINEX (eprinomectin) Pour-On may be used for human consumption at any time following treatment.

Do not use in calves intended for veal or unapproved animal species as severe adverse reaction, including fatalities in dogs, may result.

WARNING:

Keep this and all drugs out of the reach of children.

NOT FOR USE IN HUMANS.

As with any topical medication intended for treatment of animals, skin contact should be avoided. If accidental skin contact occurs, wash immediately with soap and water. If accidental eye exposure occurs, flush eyes immediately with water. The material safety data sheet (MSDS) contains more detailed occupational safety information.

To report adverse effects, obtain an MSDS or for assistance, contact Merial at 1-888-637-4251.

PRECAUTIONS

This product is for topical application only. Do not administer orally or by injection.

Do not apply to areas of the backline covered with mud or manure.

IVOMEC EPRINEX Pour-On is not recommended for use in species other than cattle. Severe adverse reactions have been reported in other species treated with products containing compounds of this class.

Restricted Drug (California) - Use only as directed.

When to Treat Cattle with Grubs

IVOMEC EPRINEX Pour-On is highly effective against all stages of cattle grubs. However, proper timing of treatment is important. For the most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season. While this is not peculiar to eprinomectin, destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions. KillingHypoderma lineatum when it is in the esophageal tissues may cause bloat; killing H. bovis when it is in the vertebral canal may cause staggering or paralysis. Cattle should be treated either before or after these stages of grub development.

Cattle treated with IVOMEC EPRINEX Pour-On at the end of the fly season may be re-treated with IVOMEC EPRINEX Pour-On during the winter without danger of grub-related reactions. For further information and advice on a planned parasite control program, consult your veterinarian.

Environmental Safety

Studies indicate that when eprinomectin comes in contact with the soil, it readily and tightly binds to the soil and becomes inactive over time. Free ivermectin/eprinomectin may adversely affect fish and certain aquatic organisms. Do not permit cattle to enter lakes, streams or ponds for at least 6 hours after treatment. Do not contaminate water by direct application or by the improper disposal of drug containers. Dispose of containers in an approved landfill or by incineration.

As with other avermectins, eprinomectin is excreted in the dung of treated animals and can inhibit the reproduction and growth of pest and beneficial insects that use dung as a source of food and for reproduction. The magnitude and duration of such effects are species and life-cycle specific. When used according to label directions, the product is not expected to have an adverse impact on populations of dung-dependent insects.

ADVERSE REACTIONS

No adverse reactions were observed during clinical trials.

STORAGE CONDITIONS

Store bottle or pack in the carton to protect from light and at temperatures up to 86°F/30°C. Storage at temperatures up to 104°F/40°C is permitted for a short period of time, however, such exposure should be minimized.

HOW SUPPLIED

IVOMEC EPRINEX (eprinomectin) Pour-On for Beef and Dairy Cattle is available in a 250 mL/8.5 fl oz (67641) or 1 L/33.8 fl oz (67643) bottle with a squeeze-measure-pour system, or in a 2.5 L/84.5 fl oz (67645) or 5 L/169 fl oz (67647) collapsible pack or 20 L/676 fl oz (67648) container intended for use with appropriate automatic dosing equipment.

Made in New Zealand

Manufactured for Merial Limited, Operational Headquarters, 3239 Satellite Blvd., Duluth, Georgia 300096-4640, U.S.A.

Manufactured to Merial Specifications by Argenta Manufacturing Limited, Manurewa, Auckland 2102, New Zealand

U.S. Pat. 4427663 and 5602107

IVOMEC and EPRINEX are registered trademarks of Merial Limited.

Copyright © 2008 Merial Limited.

All Rights Reserved.

1050-2355-02

Rev. 05-2008

NAC No.: 1111033.5
Loading...