Adequan CANINE

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by Novartis

For IM Injection - Used to control signs of osteoarthritis (Hip Dysplasia). 5ml vial.
100mg/ml (500mg per bottle).

Adequan Canine should be used with caution in dogs with renal or hepatic impairment. Possible side effects (pain at injection site, diarrhea and abnormal bleeding) were mild, transient and self-limiting. Safety studies of PSGAG in breeding, pregnant or lactating dogs have not been conducted.

Know how to spot the early signs of arthritis and the risk factors

• Observe your dog for signs of arthritis
• Tell your vet about signs you’ve observed and/or your dog’s behavior changes
• Follow your veterinarian’s treatment protocol
• Ask for Adequan® Canine to slow the disease of arthritis
• Take steps to maintain good joint health
• Keep your veterinarian updated on your dog’s progress
• Talk to your veterinarian about other ways to maintain good joint health

Description: The active ingredient in Adequan^® Canine is polysulfated glycosaminoglycan (PSGAG). Polysulfated glycosaminoglycan is a semi-synthetic glycosaminoglycan prepared by extracting glycosaminoglycans (GAGs) from bovine tracheal cartilage. GAGs are polysaccharides composed of repeating disaccharide units. The GAG present in PSGAG is principally chondroitin sulfate containing 3 to 4 sulfate esters per disaccharide unit. The molecular weight for PSGAG used in the manufacture of Adequan^® is 3,000 to 15,000 daltons. Each mL of Adequan^® Canine contains 100 mg of PSGAG, 0.9% v/v benzyl alcohol as a preservative, and water for injection q.s. to 1 mL. Sodium hydroxide and/or hydrochloric acid added when necessary to adjust pH.

Indications and Usage: Adequan^® Canine is recommended for intramuscular injection for the control of signs associated with non-infectious degenerative and/or traumatic arthritis of canine synovial joints.

Dosage and Administration: The recommended dose of Adequan^® Canine is 2 mg/lb body weight (.02 mL/lb, or 1 mL per 50 lb), by intramuscular injection only, twice weekly for up to 4 weeks (maximum of 8 injections). Do not exceed the recommended dose or therapeutic regimen. Do not mix Adequan^® Canine with other drugs or solvents.

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