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Description

E-SE (Selenium, Vitamin E) Injection is recommended for the control of the following clinical signs when associated with myositis (Selenium-Tocopherol Deficiency) syndrome: rapid respiration, profuse sweating, muscle spasms and stiffness, elevated SGOT.

Features and Benefits

• Vitamin E-selenium, injectable solution for horses only.
• Formulated to maximize efficacy
• Flexibility of slow intravenous or deep intramuscular routes of administration
• Intravenous administration if elected should be by slow injection. 

Indications

E-SE® is recommended for the control of the following clinical signs when associated with myositis (Selenium-Tocopherol Deficiency) syndrome: rapid respiration, profuse sweating, muscle spasms and stiffness, elevated SGOT.

Dosage and Administration

Administration

Administer by slow intravenous injection or deep intramuscular injections, in divided doses in two or more sites in the gluteal or cervical muscles.

Dosage

1 mL per 100 pounds of body weight. May be repeated at 5-10 day intervals.

Caution

Intravenous administration, if elected, should be by slow injection. Emulsions injected intramuscularly into the horse may produce transitory local muscle soreness and can be prevented to some degree by injecting deeply (2 to 2 1/2 inches), in divided doses, in two or more sites. Do not continue therapy in horses demonstrating such sensitivity. selenium is toxic if administered in excess. A fixed dose schedule is therefore important (read package insert for each selenium-tocopherol product carefully before using).

Warnings

Anaphylactoid reactions, some of which have been fatal, have been reported in horses administered E-SE Injection. Signs include excitement, sweating, trembling, ataxia, respiratory distress, and cardiac dysfunction. These reactions have been reported as association both with intravenous and intramuscular injections. It is presently unknown whether the mode of application affects the frequency of such reactions. However, reactions associated with intramuscular injections have been reported to manifest more slowly and hence may give more time to institute treatment for anaphylaxis, such as epinephrine and/or corticosteroid injection. Medications which have been reported to cause major adverse reactions in horses should be avoided when E-SE is administered, unless the condition of the animal requires such use. Not to be used in horses intended for food.

E-SE Injectable is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co. Inc.

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100ml vial.

Features and Benefits

• Formulated to maximize efficacy.
• Assured quantity of selenium (2.5 mg) and vitamin E (50 mg) per mL.
• Flexibility of slow intravenous or deep intramuscular routes of administration.

Indications
E-SE® is recommended for the control of the following clinical signs when associated with myositis (Selenium-Tocopherol Deficiency) syndrome: rapid respiration, profuse sweating, muscle spasms and stiffness, elevated SGOT.

Description
E-SE Injection is an emulsion of selenium-tocopherol for the prevention and treatment of myositis (Selenium-Tocopherol Deficiency) syndrome in horses. Each mL contains: 5.48 mg sodium selenite (equivalent to 2.5 mg selenium), 50 mg (68 IU) vitamin E (as d-alpha tocopheryl acetate), 250 mg polyoxyethylated vegetable oil, 2% benzyl alcohol (preservative), water for injection q.s. Sodium hydroxide and/or hydrochloric acid may be added to adjust pH.

Dosage and Administration
Administration: Administer by slow intravenous injection (see WARNINGS) or deep intramuscular injections, in divided doses in two or more sites in the gluteal or cervical muscles. Dosage: 1 mL per 100 pounds of body weight. May be repeated at 5-10 day intervals.