ClindaCure (clindamycin hydrochloride liquid) Oral Drops

Description

ClindaCure (Clindamycin Hydrochloride Oral Liquid) is indicated for the treatment of soft tissue infections (wounds and abscesses), dental infections and osteomyelitis caused by susceptible strains of Staphylococcus aureus.

CLINDACURE (Clindamycin Hydrochloride Oral Liquid) contains clindamycin hydrochloride which is the hydrated salt of clindamycin. Clindamycin is a semi-synthetic antibiotic produced by a 7(S)-chlorosubstitution of the 7(R)-hydroxyl group of a naturally produced antibiotic produced by Streptomyces lincolnensis var. lincolnensis.

ClindaCure (Clindamycin Hydrochloride Oral Liquid) is a palatable formulation intended for oral administration to dogs. Each mL of ClindaCure (Clindamycin Hydrochloride Oral Liquid) contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol, 8.64%.

Contraindications

ClindaCure (Clindamycin Hydrochloride Oral Liquid) is contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. Because of potential adverse gastrointestinal effects, do not administer to rabbits, hamsters, guinea pigs, horses, chinchillas or ruminating animals.

Warnings

Not for human use

Precautions

ClindaCure (Clindamycin Hydrochloride Oral Liquid) should be prescribed with caution in atopic animals. During prolonged therapy of one month or greater, periodic liver and kidney function tests and blood counts should be performed.

The use of clindamycin hydrochloride occasionally results in overgrowth of non-susceptible organisms such as clostridia and yeasts. Therefore, the administration of clindamycin hydrochloride should be avoided in those species sensitive to the gastrointestinal effects of clindamycin. Should superinfections occur, appropriate measures should be taken as indicated by the clinical situation.

Patients with very severe renal disease and/or very severe hepatic disease accompanied by severe metabolic aberrations should be dosed with caution, and serum clindamycin levels monitored during high-dose therapy. Clindamycin hydrochloride has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, clindamycin hydrochloride should be used with caution in animals receiving such agents. Safety in gestating bitches or breeding males has not been established.

Dosage and Administration

Approved for use in dogs and cats.

Recommended dog dosage

For therapy of wounds, abscesses and dental infections, orally administer 2.5-15 mg/lb (1-6mL/10 lb) of body weight every 12 hours. For therapy of osteomyelitis, orally administer 5.0-15.0 mg/lb (2-6 mL/10 lb) body weight every 12 hours. Duration: Treatment with clindamycin hydrochloride products may be continued up to a maximum of 28 days if clinical judgment indicates. Treatment of acute infections should not be continued for more than three or four days if no response to therapy is seen.

Recommended cat dosage

For therapy of wounds, abscesses and dental infections, orally administer 1-3 mL/5 lb of body weight once every 24 hours depending on the severity of the condition. Duration: Treatment with clindamycin hydrochloride oral solution may be continued up to a maximum of 14 days if clinical judgement indicates. Treatment of acute infections should not be continued for more than three or four days if no response to therapy is seen.

How Supplied

ClindaCure (Clindamycin Hydrochloride Oral Liquid) is available as 20 mL filled in 30 mL bottles (25 mg/mL) supplied in packers containing 12 cartoned bottles with direction labels and calibrated dosing droppers.