Cytopoint

Cytopoint
10 mg - per 1 ml vial - Sky *Cooler Item*
20 mg - per 1 ml vial - Plum *Cooler Item*
30 mg - per 1 ml vial - Blush *Cooler Item*
40 mg - per 1 ml vial - Navy *Cooler Item*
SKU : 633310_-RX
Price: $24.89
Veterinarian Prescription (Rx) Required
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  • Aids in the reduction of clinical signs associated with atopic dermatitis in dogs.
  • Ready-to-use, sterile injection that controls chronic dog itch for 4 to 8 weeks
  • Available Sizes:
    • Sky: 10 mg vial
    • Plum: 20 mg vial
    • Blush: 30 mg vial
    • Navy: 40 mg vial
This is a cooler item and it Must Ship Overnight delivery.
**Cooler Item**
RX required for this item. 
Click here for our full Prescription Policy and Form

CYTOPOINT is a safe, effective, long-lasting treatment for chronic itch due to allergic or atopic dermatitis. Cytopoint is a ready-to-use, sterile injection that controls chronic dog itch. CYTOPOINT injection starts controlling itch within one day and provides relief that lasts for 4 to 8 weeks.

CYTOPOINT
has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis.

Click here to view CYTOPOINT drug facts sheet.

BENEFITS:
  • Provides itch relief for 4 to 8 weeks
  • Heals damaged skin after just 1 injection
  • For dogs only
AVAILABLE SIZES: 
  • Sky: 10 mg vial
  • Plum: 20 mg vial
  • Blush: 30 mg vial
  • Navy: 40 mg vial
DIRECTIONS: Cytopoint is available in 1-mL vials in four concentrations (10, 20, 30 or 40 mg). Administer Cytopoint at a minimum dose of 0.9 mg/lb (2 mg/kg) body weight. For convenience, the dosing tables below may be used as a guideline. Repeat administration every 4-8 weeks as needed in individual patients. The product does not contain a preservative. Each vial is for single use only, and should be discarded after puncture.

by Pfizer-Zoetis


Because this is a cooler item, it must Ship OVERNIGHT Delivery to insure the integrity of the product. This items ships in a styrofoam cooler with ice packs on Monday-Thursdays (on orders placed before 2:00p.m.) 

 

Click here for our Vaccine Shipping Schedule.
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CYTOPOINT™

Zoetis

Canine Atopic Dermatitis Immunotherapeutic

For Use in Dogs Only

Cytopoint™ aids in the reduction of clinical signs associated with atopic dermatitis in dogs.

Cytopoint™ is a ready-to-use, sterile liquid containing a caninized monoclonal antibody (mAb) against interleukin-31 (IL-31). IL-31 has been shown to induce pruritus in dogs in laboratory studies.

Cytopoint™ remains in circulation for several weeks. It exerts a therapeutic effect by binding to and neutralizing soluble IL-31, thus inhibiting pruritus and reducing skin lesions. Like other naturally-occurring antibodies and antibody-antigen complexes, elimination is via normal protein degradation pathways.

SAFETY: A field safety study has demonstrated that Cytopoint™ is well tolerated in dogs after subcutaneous injection. Adverse events occurred at a similar frequency between treated and placebo groups in a study of 245 canine patients presented to veterinary hospitals and diagnosed with atopic dermatitis. In this study, dogs were administered Cytopoint™ (1.0-3.3 mg/kg body weight) or placebo by the subcutaneous route on Days 0 and 28. Signs of patient discomfort on administration and adverse events occurred at a similar frequency between treatment groups. In addition, there was no clinically important difference in clinical pathology changes between groups following either dose. A wide variety of concomitant medications were safely used, including parasiticides, antibiotics, antifungals, corticosteroids, vaccines, immunotherapy, antihistamines and other antipruritics, such as oclacitinib and cyclosporine.

Cytopoint™ has also been demonstrated to be well-tolerated in dogs in a laboratory safety study in which 7 consecutive monthly subcutaneous injections were administered at doses of 3.3 mg/kg or 10 mg/kg body weight (12 dogs per group).

EFFECTIVENESS: Cytopoint™ has a demonstrated onset of efficacy within 1 day and maintains efficacy for at least 1 month following a single dose in the field study.

In a study of 211 canine patients presented to veterinary hospitals and diagnosed with atopic dermatitis, a single dose of Cytopoint™ (up to 2.0 mg/kg) or placebo was administered subcutaneously. The study confirmed a significant (P<0.05) increase in the frequency of treatment success compared to placebo for at least one month at a dose of 2.0 mg/kg. Treatment success measures were based on the owner assessment of pruritus (Visual Analog Scale; VAS) scores and veterinarian assessment of skin lesion scores (Canine Atopic Dermatitis Extent and Severity Index; CADESI-03).

DIRECTIONS:

Cytopoint™ is available in 1-mL vials in four concentrations (10, 20, 30 or 40 mg). Administer Cytopoint™ at a minimum dose of 0.9 mg/lb (2 mg/kg) body weight. For convenience, the dosing tables below may be used as a guideline. Repeat administration every 4-8 weeks as needed in individual patients.

The product does not contain a preservative. Each vial is for single use only, and should be discarded after puncture.

Dogs weighing < 5.0 lb (<2.3 kg):

Aseptically withdraw 0.09 mL/lb (0.2 mL/kg) from a single, 10-mg (Sky) vial and administer subcutaneously. Discard any remaining product.

Dogs weighing 5.0-40 lb (2.3-18.1 kg):

Aseptically withdraw the full volume of the appropriate vial according to the dosage table below and administer subcutaneously.

Dog Body Weight in Pounds

Dog Body Weight in Kilograms

Presentation

10 mg (Sky)

20 mg (Plum)

30 mg (Blush)

40 mg (Navy)

5.0 - 10

2.3 - 4.5

1 vial

 

 

 

10.1 - 20

4.6 - 9.1

 

1 vial

 

 

20.1 - 30

9.2 - 13.6

 

 

1 vial

 

30.1 - 40

13.7 - 18.1

 

 

 

1 vial

Dogs weighing > 40 lb (18.1 kg):

A single dose requires a combination of vials, as outlined in the table below. Prior to administration, collect the number of vials indicated under each presentation according to the dog’s body weight.

Aseptically draw the full volume from each vial into one syringe and administer subcutaneously as a single injection.

Dog Body Weight in Pounds

Dog Body Weight in Kilograms

Presentation

10 mg (Sky)

20 mg (Plum)

30 mg (Blush)

40 mg (Navy)

40.1 - 50

18.2 - 22.7

1 vial +

 

 

1 vial

50.1 - 60

22.8 - 27.2

 

1 vial +

 

1 vial

60.1 - 70

27.3 - 31.7

 

 

1 vial +

1 vial

70.1 - 80

31.8 - 36.3

 

 

 

2 vials

80.1 - 90

36.4 - 40.8

1 vial +

 

 

2 vials

90.1 - 100

40.9 - 45.4

 

1 vial +

 

2 vials

100.1 - 110

45.5 - 49.9

 

 

1 vial +

2 vials

110.1 - 120

50.0 - 54.4

 

 

 

3 vials

120.1 - 130

54.5 - 59.0

1 vial +

 

 

3 vials

130.1 - 140

59.1 - 63.5

 

1 vial +

 

3 vials

140.1 - 150

63.6 - 68.0

 

 

1 vial +

3 vials

150.1 - 160

68.1 - 72.6

 

 

 

4 vials

160.1 - 170

72.7 - 77.1

1 vial +

 

 

4 vials

170.1 - 180

77.2 - 81.6

 

1 vial +

 

4 vials

180.1 - 190

81.7 - 86.2

 

 

1 vial +

4 vials

190.1 - 200

86.3 - 90.7

 

 

 

5 vials

PRECAUTIONS:

1. The product does not have a preservative. Each vial is for single use only, and should be discarded after puncture.

2. This product is intended for subcutaneous use only.

3. Store upright at 2°-8°C. Prolonged exposure to higher temperatures and/or direct sunlight may adversely affect potency. Do not freeze.

4. Use entire contents when first opened.

5. Sterilized syringes and needles should be used to administer this product. Do not sterilize with chemicals because traces of disinfectant may inactivate the product.

6. This product has not been tested in pregnant, lactating or breeding animals.

For use by, or under the supervision of, a veterinarian.

Technical inquiries should be directed to Zoetis Inc. Veterinary Services, (888) 963-8471 (USA), (800) 461-0917 (Canada).

This product has been shown to be efficacious in treating healthy dogs with canine atopic dermatitis.

U.S. Veterinary License No. 190

Zoetis Inc., Kalamazoo, MI 49007, USA

50120600

CPN: 3690566.0

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