Zylexis 2ml bottle
2ml - single vial
Must ship overnight

2ml (5-pack) - pack of 5 ($41.40/each)
Must ship overnight

SKU : 95252
Price: $43.50

For upper respiratory disease in horses

2ml - No RX Required
On manufacturer backorder

by Zoetis

Why Zylexis?


  • Aids in the reduction of upper respiratory disease associated with equine herpesvirus types 1 and 4
  • ZYLEXIS treated horses showed significantly lower purulent nasal discharge (p<0.01) and clinical signs (p<0.01) than non-treated control horses1
  • Less days of mucopurulent nasal discharge were seen in ZYLEXIS treated horses vs. the control group1
  • Decreased nasal discharge scores may indicate less bacterial infections following EHV 1 & 4 infections


  • A study of the Parapox Ovis Virus Immunomodulator in horses has shown an improvement in immune response that is useful in reducing severity and duration of viral disease2
  • Parapox Ovis Virus activates immune cells, stimulates phagocytosis and induces expression of cytokines; the messenger proteins that stimulate production of interferon and immune cells in a number of species3,4,5,6,7


  • None of the three-hundred and thirty-three ZYLEXIS treated horses had visible or palpable reactions at the injection site or systemic reactions8
  • ZYLEXIS is indicated for use in healthy horses over 4 months of age

  • Aseptically rehydrate the freeze-dried component with the sterile diluent provided
  • Shake well and administer 2mL intramuscularly
  • Repeat the 2mL dose on days 2 and 9 following the initial dose

Because this is a cooler item, it must Ship OVERNIGHT Delivery to insure the integrity of the product. This items ships in a styrofoam cooler with ice packs on Monday-Thursdays (on orders placed before 2:00p.m.) 

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Parapox Ovis Virus Immunomodulator

For use in healthy horses 4 months of age or older as an aid in reducing upper respiratory disease caused by equine herpesvirus types 1 and 4. Zylexis is an immunostimulant consisting of inactivated Parapox ovis virus.

Directions: Aseptically rehydrate the freeze-dried component with the sterile diluent provided, shake well and administer 2 mL intramuscularly. Repeat the 2-mL dose on days 2 and 9 following the initial dose. Retreatment is recommended during subsequent disease episodes or prior to stress-inducing situations.

Precautions: Store at 2°-8°C. Do not freeze. Use entire contents when first opened. Sterilized syringes and needles should be used to administer this vaccine. Do not vaccinate within 21 days before slaughter. In case of anaphylaxis, administer epinephrine or equivalent.

Mfd. by: Bayer A.G. Animal Division, D-50739 Cologne, Germany

Dist. by: Zoetis Inc., Kalamazoo, MI 49007

U.S. Permit No. 189C

5 x 1 dose vials of vaccine

Rehydrate to 2 ml

5 x 2 ml vials of sterile diluent

For use in horses only


NAC No.: 3690229.2