Animax Ointment

Animax Ointment combines nystatin, neomycin sulfate, thiostrepton and triamcinolone acetonide in a non-irritating polyethylene and mineral oil base.

Each mL contains: nystatin 100,000 units, neomycin sulfate equivalent to neomycin base 2.5mg, thiostrepton 2,500 units, triamcinolone acetonide 1 mg.

The preparation is intended for local therapy in a variety of cutaneous disorders of dogs and cats; it is especially useful in disorders caused, complicated, or threatened by bacterial and/or candidal (monilial) infection.

Key Benefits

• Combines anti-inflammatory, antibacterial, anti-fungal, and anti-itch medications in one convenient prescription
• Kills harmful organisms and provides quick symptom relief
• Effectively treats a range of ailments
• Easy to apply ointment for the skin or ears

How it works

Animax contains key ingredients Nystatin, Neomycin Sulfate, Thiostrepton and Triamcinolone Acetonide. Triamcinolone Acetonide is a corticosteroid which provides quick symptomatic relief when applied topically. Nystatin is an antifungal antibiotic which helps with the treatment of skin infections caused by Candida albicans, a type of skin fungus. Neomycin sulfate works as an antimicrobial agent against gram-negative and gram-positive bacteria. Thiostrepton is an antibiotic which can fight against gram-positive organisms, including most which are resistant to other antibiotics. When combined, these ingredients help to prevent bacterial infections caused by certain organisms.

Indications

Animax Ointment is particularly useful in the treatment of acute and chronic otitis of varied etiologies, in interdigital cysts in cats and dogs and in anal gland infections in dogs. The preparation is also indicated in the management of dermatologic disorders characterized by inflammation and dry or exudative dermatitis, particularly those caused, complicated, or threatened by bacterial or candidal (Candida albicans) infections. It is also of value in eczematous dermatitis, contact dermatitis, and seborrheic dermatitis; and as an adjunct in the treatment of dermatitis due to parasitic infestation.

Directions

Frequency of administration is dependent on the severity of the condition. For mild inflammations, application may range from once daily to once a week; for severe conditions Animax Ointment may be applied as often as two to three times daily, if necessary. Frequency of treatment may be decreased as improvement occurs. Wear gloves during the administration of the ointment or wash hands immediately after application.

Otitis

Clean ear canal of impacted cerumen. Inspect canal and remove any foreign bodies such as grass awns, ticks, etc. Instill three to five drops of Animax Ointment. Preliminary use of a local anesthetic may be advisable.

Infected Anal Glands, Cystic Areas, etc.

Drain gland or cyst and then fill with Animax Ointment.

Other Dermatologic Disorders

Clean affected areas, removing any encrusted discharge or exudate. Apply Animax Ointment (Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment) sparingly in a thin film.

Caution

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Warnings

Clinical and experimental data have demonstrated that corticosteroids administered orally or by injection to animals may induce the first stage of parturition if used during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis.

Additionally, corticosteroids administered to dogs, rabbits and rodents during pregnancy have resulted in cleft palate in the offspring. In dogs, other congenital anomalies have resulted: deformed forelegs, phocomelia, and anasarca.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Precautions

Animax Ointment is not intended for the treatment of deep abscesses or deep-seated infections such as inflammation of the lymphatic vessels. Parenteral antibiotic therapy is indicated in these infections. Animax Ointment (Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment) has been extremely well tolerated. Cutaneous reactions attributable to its use have been extremely rare. The occurrence of systemic reactions is rarely a problem with topical administration. There is some evidence that corticosteroids can be absorbed after topical application and cause systemic effects. Therefore, an animal receiving Animax Ointment therapy should be observed closely for signs such as polydipsia, polyuria, and increased weight gain. Animax Ointment is not generally recommended for the treatment of deep or puncture wounds or serious burns.Sensitivity to neomycin may occur. If redness, irritation, or swelling persists or increases, discontinue use. Do not use if pus is present since the drug mayallow the infection to spread. Avoid ingestion. Oral or parenteral use ofcorticosteroids (depending on dose, duration of use, and specific steroid) may result in inhibition of endogenous steroid production following drug withdrawal.

Side Effects

SAP and SGPT (ALT) enzyme elevations, polydipsia and polyuria, vomiting, and diarrhea (occasionally bloody) have been observed following parenteral or systemic use of synthetic corticosteroids in dogs.Cushing’s syndrome has been reported in association with prolonged or repeated steroid therapy in dogs. Temporary hearing loss has been reported in conjunction with treatment of otitis with products containing corticosteroids. However, regression usually occurred following withdrawal of the drug.Hearing loss, with varying degrees of recovery, has been reported with the use of Animax Ointment. If hearing dysfunction is noted during the course of treatment with Animax Ointment, discontinue its use.

Caution

Before instilling any medication into the ear, examine the external ear canal thoroughly to be certain the tympanic membrane is not ruptured in order to avoid the possibility of transmitting infection to the middle ear as well as damaging the cochlea or vestibular apparatus from prolonged contact.If hearing or vestibular dysfunction is noted during the course of treatment, discontinue the use of Animax Ointment.

Storage

Store at room temperature; avoid excessive heat (104°F).240 mL bottle: Do not store above 86°F.

Animax Ointment combines nystatin, neomycin sulfate, thiostrepton and triamcinolone acetonide in a non-irritating polyethylene and mineral oil base.

Each mL contains: nystatin 100,000 units, neomycin sulfate equivalent to neomycin base 2.5mg, thiostrepton 2,500 units, triamcinolone acetonide 1 mg.

The preparation is intended for local therapy in a variety of cutaneous disorders of dogs and cats; it is especially useful in disorders caused, complicated, or threatened by bacterial and/or candidal (monilial) infection.

INDICATIONS
Animax Ointment is particularly useful in the treatment of acute and chronic otitis of varied etiologies, in interdigital cysts in cats and dogs and in anal gland infections in dogs.

The preparation is also indicated in the management of dermatologic disorders characterized by inflammation and dry or exudative dermatitis, particularly those caused, complicated, or threatened by bacterial or candidal (Candida albicans) infections. It is also of value in eczematous dermatitis, contact dermatitis, and seborrheic dermatitis; and as an adjunct in the treatment of dermatitis due to parasitic infestation.

DOSAGE AND ADMINISTRATION
Frequency of administration is dependent on the severity of the condition. For mild inflammations, application may range from once daily to once a week; for severe conditions Animax Ointment may be applied as often as two to three times daily, if necessary. Frequency of treatment may be decreased as improvement occurs.

Wear gloves during the administration of the ointment or wash hands immediately after application.