INDICATIONS AND USAGE
Cefazolin powder for injection is indicated in the treatment of the following serious infections due to susceptible organisms:
Respiratory Tract Infections:
Due to S.pneumoniae, Klebsiella species, H.influenzae, S.aureus (penicillin-sensitive and penicillin-resistant), and group A beta-hemolytic strep-tococci. Injectable benzathine penicillin is considered to be the drug of choice in treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever. Cefazolin is effective in the eradication of streptococci from the nasopharynx; however,data establishing the efficacy of cefazolin in the subsequent prevention of rheumatic fever are not available at present.
Urinary Tract Infections:
Due to E. coli, P.mirabilis, Klebsiellaspecies, and some strains of enterobacter and enterococci.
Skin and Skin Structure Infections:
Due to S.aureus (penicillin-sensitive and penicillin-resistant), group A beta-hemolytic streptococci, and other strains of streptococci.
Biliary Tract Infections:
Due to E.coli, various strains of streptococci, P.mirabilis,Klebsiella species, and S. aureus.
Bone and Joint Infections:
Due to S. aureus.
(i.e., prostatitis, epididymitis) due to E.coli, P.mirabilis, Klebsiellaspecies, and some strains of enterococci.
Due to S. pneumoniae, S. aureus(penicillin-sensitive and penicillin-resist-ant), P.mirabilis, E. coli, and Klebsiella species.
: Due to S.aureus(penicillin-sensitive and penicillin-resistant) and group Abeta-hemolytic streptococci.