Free shipping over $75!

Surpass Topical Cream 1%


Surpass Topical Cream 1% - 124gm Tube


Surpass Topical Cream 1% - 124gm Tube

SKU: 3129124-RX
Out of stock
Price: $56.95
  • Vet RX Required.
  • 124gm Surpass Topical Cream Contains 1% diclofenac sodium.
  • Control pain and inflammation associated with osteoarthritis in the hock, knee, fetlock and pastern joints in horses.
  • On manufacturer backorder. Check back soon!
RX required for this item.
Click here for our full Prescription Policy and Form

by Boehringer

Watch for new packaging:

Description
Surpass Topical Cream Contains 1% diclofenac sodium. Diclofenac is a nonsterodial anti-inflammatory drug of the phenylacetic acid class.


Features

  • Patented WISDOM™ liposomal delivery system.
  • Convenient topical application.
  • Minimal systemic absorption.
  • No bandage is required
Benefits
  • Novel approach for the relief of equine pain due to osteoarthritis inflammation.
  • Cream formulation is easily applied in minutes.
  • Improves horse owner compliance.
  • No bandage is required
Advantages
SURPASS topical cream provides direct relief of pain and inflammation associated with equine osteoarthritis in tarsal, carpal, metacarpophalangeal, metatarsophalangeal and proximal interphalangeal (hock, knee, fetlock and pastern) joints in horses.

Dosage & Administration
Apply a five-inch (5”) ribbon of SURPASS topical cream twice daily over the affected joint for up to ten days. One tube will treat one horse for ten days. Rub the cream thoroughly into the hair covering the joint until it disappears.
Product Rating: (0.00)   # of Ratings: 0   (Only registered customers can rate)

There are no comments for this product.

SURPASS® TOPICAL CREAM

Boehringer Ingelheim

(1% diclofenac sodium)

Topical Anti-Inflammatory Cream

For Use in Horses

NADA 141-186, Approved by FDA

Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Description: Surpass® topical cream contains 1% diclofenac sodium. Diclofenac is a non-steroidal anti-inflammatory drug of the phenylacetic acid class. The chemical name for diclofenac is sodium [o- (2,6-dichloroanilino)phenyl]acetate. The empirical formula is C14H10Cl2NNaO2 and the molecular weight is 318.13. Surpass topical cream contains 1% diclofenac sodium in a base composed of Phospholipon 90H, propylene glycol, alcohol (5.94%), vitamin E acetate, benzethonium chloride and purified water in the Wisdom® liposomal formulation.

Indications: Surpass topical cream is indicated for the control of pain and inflammation associated with osteoarthritis (OA) in tarsal, carpal, metacarpophalangeal, metatarsophalangeal and proximal interphalangeal (hock, knee, fetlock and pastern) joints in horses.

Dosage and Administration: Always provide the Client Information Sheet with the prescription.

Dosage: Apply a five-inch (5”) ribbon of Surpass topical cream twice daily over the affected joint for up to ten days.

Administration: Wear rubber gloves to prevent absorption into the hands. Rub the cream thoroughly into the hair covering the joint until it disappears.

Contraindications: Surpass topical cream is contraindicated in animals with known hypersensitivity to diclofenac.

Warnings: Not for horses intended for human consumption.

User Safety: Keep out of reach of children. Not for human use. Consult a physician in case of accidental ingestion by humans.

Wear gloves to prevent absorption into the hands. Direct contact with the skin should be avoided. If contact occurs, the skin should be washed immediately with soap and water.

Animal Safety: For topical use in horses only. Owners should be advised to observe for signs of potential drug toxicity (see Information for Owner or Person Treating Animal and Adverse Reactions).

Precautions: Exceeding the recommended dosage or treating multiple joints may increase plasma concentrations of diclofenac (see Animal Safety). The systemic effects of excess diclofenac doses that exceed the recommended label amount and duration have not been evaluated.

Horses should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests should be conducted to establish hematological and serum biochemical baseline data before and periodically during administration of any NSAID. Owners should be advised to observe for signs of potential drug toxicity (see Information for Owner or Person Treating Animal).

Treatment with Surpass cream should be terminated if signs such as inappetence, colic, fecal abnormalities, anemia or depression are observed.

As a class, NSAIDs may be associated with gastrointestinal and renal toxicity. When NSAIDs inhibit prostaglandins that cause inflammation, they may also inhibit prostaglandins that maintain normal homeostatic function. These anti-prostaglandin effects may result in clinically significant disease in patients with underlying or preexisting disease more often than in healthy patients. Patients at greatest risk for renal toxicity are those that are dehydrated, on concomitant diuretic therapy, or those with renal, cardiovascular and/or hepatic dysfunction.

Studies to determine the effect of Surpass topical cream when administered concomitantly with other drugs have not been conducted. Since many NSAIDs possess the potential to induce gastric ulceration, concomitant use of Surpass cream with any other anti-inflammatory drugs, such as other NSAIDs and corticosteroids, should be avoided. Drug compatibility should be monitored closely in patients receiving adjunctive therapy.

The safety of Surpass cream has not been investigated in breeding, pregnant or lactating horses, or in horses under one year of age.

Adverse Reactions: During the field study, one diclofenac-treated horse developed colic on day four of the study and responded to symptomatic treatment. One placebo-treated horse exhibited mildly jaundiced mucous membranes on day five. Adverse reactions during the safety study included a gastric ulcer in one horse that received 5.6X the recommended dosage, diarrhea and uterine discharge in one horse that received 2.8X the recommended dosage, and weight loss in four of the six horses in the 5.6X dosage group.

To report suspected adverse reactions, to obtain a Material Safety Data Sheet or for technical assistance, call 1-866-638-22261-866-638-2226 FREE.

Information For Owner or Person Treating Animal: Owners should be advised of the potential for adverse reactions and be informed of the clinical signs associated with NSAID intolerance. Adverse reactions may include: weight loss, colic, diarrhea, or icterus. Serious adverse reactions associated with this drug class can occur without warning and, in rare situations, result in death. Owners should be advised to discontinue NSAID therapy and contact their veterinarian immediately if signs of intolerance are observed. The majority of patients with drug-related adverse reactions recover when the signs are recognized, drug administration is stopped, and veterinary care is initiated.

Clinical Pharmacology: Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. The mechanism of action of diclofenac, like other NSAIDs, is believed to be associated with the inhibition of cyclooxygenase activity.

Effectiveness: In a controlled field study, 82 horses with osteoarthritis were treated with Surpass topical cream (42 horses) or placebo (40 horses). Lameness examinations were performed in horses with osteoarthritis associated with the tarsal, carpal, metacarpophalangeal, metatarsophalangeal and proximal interphalangeal joints. Investigators were masked to treatment. Investigators and owners were instructed to apply the test article over the affected joint twice daily (BID) for five days. Actual doses received by individual horses were calculated using tube weight measurements. The mean dose applied during the study was 73 mg per application. Average lameness scores showed statistically significant improvement following treatment with Surpass topical cream.

One diclofenac-treated horse developed colic and responded to symptomatic treatment on day four of the study. Day five bloodwork for the horse that colicked showed decreases in RBC, Hb and HCT, with an increase in PMNs, compared to pretreatment values. One placebo-treated horse exhibited mildly jaundiced mucous membranes on day five. No other adverse reactions were noted during the study.

Animal Safety: A controlled safety study was conducted with Surpass topical cream. Four groups of six healthy adult horses received 0, 0.6, 1.7 or 2.8X the recommended daily dose for twenty-eight days. The daily dose was divided into two applications on day one of the study. For the remainder of the study, the entire daily dose was given at one time on 0, 1, 3 or 5 joints (tarsal, carpal, metacarpophalangeal, metatarsophalangeal, and proximal interphalangeal joints), depending on the dosage group. The control group of six horses was sham-dosed by rubbing the joints daily for twenty-eight days. An additional study group evaluated six horses that received 5.6X the recommended daily dose of Surpass topical cream distributed over five joints on a single day. This dose group was observed for fourteen days without additional treatment.

Clinical examinations, hematology, serum chemistry, synovial fluid analyses, gross necropsy and histopathology were performed. At necropsy, one horse in the 5.6X group had a glandular gastric ulcer. A horse in the 2.8X group had diarrhea and uterine discharge throughout the study. Four of the six horses in the 5.6X group lost weight during the study.

Dose-dependent increases in diclofenac plasma concentrations were detected in horses in the 1.7X and 2.8X treatment groups.

Storage Information: Store at up to 25°C (77°F). Protect from freezing.

How Supplied: Surpass topical cream is white to pinkish-white and is packaged in 124-gram trilaminate tubes.

Surpass and Wisdom are registered trademarks of Boehringer Ingelheim Vetmedica, Inc.

Manufactured for: Boehringer Ingelheim Vetmedica, Inc., St. Joseph, MO 64506 U.S.A.

Manufactured under U.S. Patent Nos. 4,937,078 and 6,936,273.

© 2009 Boehringer Ingelheim Vetmedica, Inc.

All Rights Reserved.

449801L-00-0901

Revised 01/2009

Code 449811

NAC No.: 1028174.0

IMPORTANT VETERINARIAN INFORMATION
We are unable to ship prescriptions into Arkansas, Louisiana, Georgia, Mississippi,
and North Carolina
*Required Information. Please complete form for each pet:













*Would you like us to contact your veterinarian for this prescription?








Low Price Guarantee

If the item has this emblem, we will gladly match any competitors’ current advertised price.

Competitor must be based in the United States, sorry we cannot honor foreign country prices.

Learn more

Fast & Free Shipping

Orders received before 1:00pm M-F (CST) will be processed that same business day.

Free shipping on non-vaccine orders of $75 or more (before tax).

Learn more

Satisfaction Guarantee

Every purchase you make at HeartlandVetSupply.com is covered by our satisfaction guarantee.

If you are not completely satisfied, please contact us within 30 days.

Learn more

Vet-VIPPS Accredited Pharmacy

Heartland Veterinary Supply & Pharmacy is a Vet-VIPPS Accredited Pharmacy

Learn more

employees

Located in Hastings, Nebraska, Heartland Veterinary Supply & Pharmacy started as a Veterinary Clinic in 1981, specializing in the health and wellness of the equine, canine and feline species. We have a licensed Veterinarian and Pharmacist on site, as well as a helpful team with the knowledge and products you need to keep your horse, dog or cat healthy and happy. The Heartland Staff is dedicated to fast, courteous service.

"Because buying prescription drugs from the Internet is easy, finding a safe source for those medicines is not."

See what our customers are saying.

Shipping Policy
Return Policy
Request Catalog

Connect

Follow Us on Pinterest
Instagram

Contact us

  • Phone: 800-934-9398
  • Fax: 888-424-0484
  • Email: info@heartlandvetsupply.com
  •  
  • HeartLandVetSupply
  • 401 W. 33rd Street
  • Hastings, NE 68901

Connecticut, Delaware, New Hampshire, New Jersey, New York, Illinois

office

© HeartlandVetSupply.com 2015. All Rights Reserved