Doxycycline hyclate is a broad-spectrum antibiotic synthetically derived from oxytetracycline. To reduce the development of drug-resistant bacteria and maintain effectiveness of doxycycline hyclate and other antibacterial drugs, doxycycline hyclate should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.
Doxycycline is an antibiotic used for treating bacterial infections
including Potomac Horse Fever,
and Lyme disease.
Doxycycline generally has similar
activity to other forms of tetracyclines against susceptible organisms,
but some strains of bacteria may be more susceptible to doxycycline.
Important Note: Intravenous injection of doxycycline has been associated with cardiac arrhythmia, collapse, and death in horses.
See Doxy side effects under Product Label tab.
Doxycycline is available in either a capsule or tablet, in various sizes. See above.
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Photosensitivity and, rarely, liver damage and blood disorders have occurred with doxycycline use.
Long-term use of doxycycline may result in overgrowth of non-susceptible bacteria or fungi.
Due to the possibility of fatalities, intravenous injections should not be used in horses until further studies documenting the safety of intravenous doxycycline in horses are conducted.
Because doxycycline can retard fetal skeletal development and discolor deciduous teeth, it should be used only in the last half of a mare's pregnancy and benefits should outweigh fetal risks.
Doxycyline is a prescription drug restricted to use by or on the lawful written or oral order of a licensed veterinarian.
Check with the appropriate individual regulatory body regarding use in competition horses.
Oral antacids, saline cathartics, and other GI products containing aluminum, calcium, magnesium, zinc, or bismuth decrease the absorption of doxycycline. Oral doxycycline should be given at least 1 to 2 hours before or after products containing these ingredients.
Oral sodium bicarbonate, kaolin pectin, or bismuth susalicylate may impair doxycycline absorption when given together orally.
Doxycycline may interfere with bactericidal activity of penicillins, cephalosporins, and aminoglycosides.
Doxycycline may increase the bioavailability of digoxin and lead to digoxin toxicity. When used in horses on anticoagulant therapy with medications such as warfarin, dosages may need adjustment.
Doxycycline may cause falsely elevated values of urine catecholamines and may cause false-positive urine glucose results, depending on the method of testing urine glucose.
Oral use of doxycycline in horses is quite safe. Any overdose may create digestive disturbances, such as diarrhea. Should a horse develop severe diarrhea, fluids and electrolytes should be monitored and replaced if necessary.
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Located in Hastings, Nebraska, Heartland Veterinary Supply & Pharmacy started as a Veterinary Clinic in 1981, specializing in the health and wellness of the equine, canine and feline species. We have a licensed Veterinarian and Pharmacist on site, as well as a helpful team with the knowledge and products you need to keep your horse, dog or cat healthy and happy. The Heartland Staff is dedicated to fast, courteous service.
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