Dicural Tablets

Dicural Tablets
11.4mg - 100 tablets
45.4mg - 100 tablets
SKU : 2913_-RX
Price: $94.95
RX required for this item.
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Antibiotics for dogs.

Dicural® (difloxacin HCl) is a fluoroquinolone antibiotic offering veterinarians once-per-day dosing to treat urinary tract infections (cystitis) and skin infections (superficial pyoderma). With Dicural®, effective bactericidal levels are reached within 30 minutes, with high bactericidal plasma levels maintained for up to 24 hours. Veterinarians benefit from the sustained bactericidal efficacy and flexible dosing of Dicural®, allowing them to safely regulate the amount of difloxacin administered. Dicural® features a long elimination half-life, meaning the drug is slowly eliminated from the body and is available to treat infection.

DOSAGE AND ADMINISTRATION: The dose range of difloxacin in dogs is 5 to 10 mg/kg body weight (2.3 to 4.6 mg/lb) once a day for two to three days beyond the cessation of clinical signs to a maximum of 30 days (see DRUG INTERACTIONS).

The determination of dosage for any particular patient must take into consideration such factors as the severity and nature of the infection, the susceptibility of the causative organism, and the integrity of the host-defense mechanisms. The dose of 5 mg/kg of body weight administered once daily should be used for the routine treatment of infection caused by susceptible organism(s) in an otherwise healthy dog. The dosage may be increased to the upper limit of the dose range (10 mg/kg), if deemed necessary. Antibiotic susceptibility of the pathogenic organism(s) should be determined prior to use of difloxacin. However, therapy with DICURAL® tablets may be initiated before results of these tests are known. Once test results become available, continue with appropriate therapy.

For the treatment of skin and soft tissue infections, DICURAL® tablets should be given for two (2) to three (3) days beyond the cessation of clinical signs to a maximum of 30 days. For the treatment of urinary tract infections, DICURAL® tablets should be administered for at least 10 consecutive days. If no improvement is noted within five (5) days, the diagnosis should be re-evaluated and a different course of therapy considered.

Table 1. Dose Table for DICURAL® tablets for Dogs

Tablet Color

Tablet Strength
(Difloxacin Base)

Daily Dose

5 mg/kg

10 mg/kg


11.4 mg

2.3 kg (5 lb)

1.1 kg (2.5 lb)


45.4 mg

9 kg (20 lb)

4.5 kg (10 lb)


136 mg

27 kg (60 lb)

13.5 kg (30 lb)


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