Vetoryl
Vetoryl by Dechra
Vetoryl is for the treatment of pituitary-dependent and adrenal-dependent hyperadrenocorticism (cushing's disease and syndrome) in dogs. Vetoryl comes in 10mg, 30mg and 60mg capsules for dogs. Vetoryl is also available in a 5mg compounded capsule.
Dosage for Vetoryl
Table 1: Starting dose
|
Weight range (pounds) |
Weight range (kg) |
Starting dose (mg) ONCE DAILY |
|
≥3.8 to <10 |
≥1.7 to <4.5 |
10 |
|
≥10 to <22 |
≥4.5 to <10 |
30 |
|
≥22 to <44 |
≥10 to <20 |
60 |
|
≥ 4 to <88 |
≥20 to <40 |
120 (2 x 60 mg) |
|
≥88 to <132* |
≥40 to <60* |
180 (3 x 60 mg) |
*Dogs over 132 pounds (60 kg) should be administered the appropriate combination of capsules.
After approximately 10-14 days at this dose, re-examine the dog and conduct a 4-6 hour post-dosing ACTH stimulation test. If physical examination is acceptable, take action according to Table 2.
Table 2: Action at 10-14 day evaluation
|
Post-ACTH serum cortisol |
Action |
|
|
µg/dL |
nmol/L |
|
|
<1.45 |
<40 |
Stop treatment. Re-start at a decreased dose |
|
1.45 to 5.4 |
40 to 150 |
Continue on same dose |
|
>5.4 to 9.1 |
>150 to 250 |
EITHER: Continue on current dose if clinical signs are well controlled OR: Increase dose if clinical signs of hyperadrenocorticism are still evident* |
|
>9.1 |
>250 |
Increase initial dose |
|
