Vetoryl  by Dechra

Vetoryl is for the treatment of pituitary-dependent and adrenal-dependent hyperadrenocorticism (cushing's disease and syndrome) in dogs. Vetoryl comes in 10mg, 30mg and 60mg capsules for dogs. Vetoryl is also available in a 5mg compounded capsule.

Dosage for Vetoryl

Table 1: Starting dose

Weight range (pounds)

Weight range (kg)

Starting dose (mg) ONCE DAILY

≥3.8 to <10

≥1.7 to <4.5

10

≥10 to <22

≥4.5 to <10

30

≥22 to <44

≥10 to <20

60

≥ 4 to <88

≥20 to <40

120 (2 x 60 mg)

≥88 to <132*

≥40 to <60*

180 (3 x 60 mg)

*Dogs over 132 pounds (60 kg) should be administered the appropriate combination of capsules.

After approximately 10-14 days at this dose, re-examine the dog and conduct a 4-6 hour post-dosing ACTH stimulation test. If physical examination is acceptable, take action according to Table 2.

Table 2: Action at 10-14 day evaluation

Post-ACTH serum cortisol

Action

µg/dL

nmol/L

<1.45

<40

Stop treatment. Re-start at a decreased dose

1.45 to 5.4

40 to 150

Continue on same dose

>5.4 to 9.1

>150 to 250

EITHER: Continue on current dose if clinical signs are well controlled

OR: Increase dose if clinical signs of hyperadrenocorticism are still evident*

>9.1

>250

Increase initial dose




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